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HE4 Tumor Marker Blood Test

Maryland rates for HCPCS 86305

A blood test that measures human epididymis protein 4, a substance often raised in women with ovarian cancer. It is used together with other tests when assessing a mass on an ovary, and to follow how a known ovarian cancer responds to treatment.

Rates data updated July 2026.

How much does HE4 Tumor Marker Blood Test cost?

$15.49

Typical negotiated rate. In Maryland, July 2026.

Insurers have agreed to pay about $15.49 for this service. Most negotiated rates run $13.80 to $20.89.

These are rates insurers have negotiated with providers, not the amount a patient is billed. What you owe depends on your plan's deductible and coinsurance. Based on rates published by 6 insurance carriers under federal price transparency rules.

How much rates vary

Facilitymedian $14 · 10th to 90th $9 to $28Professionalmedian $15 · 10th to 90th $13 to $30
$10$20$50$100facility $14professional $15

Distribution of negotiated rates across all payers (price axis is log-scale). Each curve is scaled to its own total: facility and professional rates are different services, shown together to compare where they cluster. Small sample; interpret with caution. Need provider-level prices or 24+ months of history? Contact us.

Rates by insurance carrier

Insurance Carrier
Aetna
Setting
Professional
Modifier
Global
Typical Low
$13.80
Median
$15.49
Typical High
$29.51
CareFirst
Setting
Professional
Modifier
Global
Typical Low
$7.41
Median
$16.60
Typical High
$20.42
Cigna
Setting
Facility
Modifier
Global
Typical Low
$10.96
Median
$14.45
Typical High
$27.54
Cigna
Setting
Professional
Modifier
Global
Typical Low
$11.48
Median
$21.88
Typical High
$51.29
Kaiser Permanente
Setting
Professional
Modifier
Global
Typical Low
$19.95
Median
$23.99
Typical High
$30.90
United
Setting
Facility
Modifier
Global
Typical Low
$8.71
Median
$9.77
Typical High
$15.85
United
Setting
Professional
Modifier
Global
Typical Low
$9.33
Median
$12.59
Typical High
$19.50
Wellpoint
Setting
Professional
Modifier
Global
Typical Low
$8.13
Median
$14.45
Typical High
$30.90

Where Maryland sits

The same service costs 3.2 times more in Oklahoma than in Washington, DC. Every bar is a state, most expensive first. Touch or drag across it to read any state, then open that state for its carriers and full range.

Maryland· 50th of 51

$15.49

OK $50.12DC $15.49

Median negotiated rate in each state, from every insurer that publishes one. States where no insurer publishes a rate for this service are not shown.