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HE4 Tumor Marker Blood Test

Illinois rates for HCPCS 86305

A blood test that measures human epididymis protein 4, a substance often raised in women with ovarian cancer. It is used together with other tests when assessing a mass on an ovary, and to follow how a known ovarian cancer responds to treatment.

Rates data updated July 2026.

How much does HE4 Tumor Marker Blood Test cost?

$18.62

Typical negotiated rate. In Illinois, July 2026.

Insurers have agreed to pay about $18.62 for this service. The price depends on where it is billed: about $16.22 from a physician practice, and about $32.36 from a hospital or other facility. The two figures are alternatives, not parts of one bill.

These are rates insurers have negotiated with providers, not the amount a patient is billed. What you owe depends on your plan's deductible and coinsurance. Based on rates published by 7 insurance carriers under federal price transparency rules.

Where it's billed changes the price

Billed byTypicalRange
Physician practiceA doctor's office, clinic or independent provider$16.22$14.45 to $21.38
FacilityA hospital or hospital-owned outpatient department$32.36$21.38 to $42.66

How much rates vary

Facilitymedian $32 · 10th to 90th $18 to $58Professionalmedian $16 · 10th to 90th $3 to $43
$5$10$20$50$100$200facility $32professional $16

Distribution of negotiated rates across all payers (price axis is log-scale). Each curve is scaled to its own total: facility and professional rates are different services, shown together to compare where they cluster. Need provider-level prices or 24+ months of history? Contact us.

Rates by insurance carrier

Insurance Carrier
Aetna
Setting
Facility
Modifier
Global
Typical Low
$16.98
Median
$32.36
Typical High
$47.86
Aetna
Setting
Professional
Modifier
Global
Typical Low
$16.22
Median
$17.78
Typical High
$42.66
Ambetter
Setting
Professional
Modifier
Global
Typical Low
$12.88
Median
$12.88
Typical High
$12.88
BCBS
Setting
Facility
Modifier
Global
Typical Low
$26.30
Median
$85.11
Typical High
$263.03
BCBS
Setting
Professional
Modifier
Global
Typical Low
$3.47
Median
$14.45
Typical High
$15.85
Cigna
Setting
Facility
Modifier
Global
Typical Low
$23.44
Median
$47.86
Typical High
$95.50
Cigna
Setting
Professional
Modifier
Global
Typical Low
$10.96
Median
$23.99
Typical High
$38.02
Hally Health
Setting
Professional
Modifier
Global
Typical Low
$21.88
Median
$56.23
Typical High
$346.74
Hally Health
Setting
Facility
Modifier
Global
Typical Low
$100.00
Median
$100.00
Typical High
$100.00
Hally Health
Setting
Professional
Modifier
Global
Typical Low
$26.92
Median
$26.92
Typical High
$26.92
Molina
Setting
Professional
Modifier
Global
Typical Low
$10.47
Median
$11.48
Typical High
$26.30
United
Setting
Facility
Modifier
Global
Typical Low
$14.79
Median
$20.89
Typical High
$41.69
United
Setting
Professional
Modifier
Global
Typical Low
$8.71
Median
$14.79
Typical High
$20.89

Where Illinois sits

The same service costs 3.2 times more in Oklahoma than in Washington, DC. Every bar is a state, most expensive first. Touch or drag across it to read any state, then open that state for its carriers and full range.

Illinois· 40th of 51

$18.62

OK $50.12DC $15.49

Median negotiated rate in each state, from every insurer that publishes one. States where no insurer publishes a rate for this service are not shown.