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HE4 Tumor Marker Blood Test

Iowa rates for HCPCS 86305

A blood test that measures human epididymis protein 4, a substance often raised in women with ovarian cancer. It is used together with other tests when assessing a mass on an ovary, and to follow how a known ovarian cancer responds to treatment.

Rates data updated July 2026.

How much does HE4 Tumor Marker Blood Test cost?

$25.12

Typical negotiated rate. In Iowa, July 2026.

Insurers have agreed to pay about $25.12 for this service. The price depends on where it is billed: about $19.95 from a physician practice, and about $32.36 from a hospital or other facility. The two figures are alternatives, not parts of one bill.

These are rates insurers have negotiated with providers, not the amount a patient is billed. What you owe depends on your plan's deductible and coinsurance. Based on rates published by 7 insurance carriers under federal price transparency rules.

Where it's billed changes the price

Billed byTypicalRange
Physician practiceA doctor's office, clinic or independent provider$19.95$15.85 to $50.12
FacilityA hospital or hospital-owned outpatient department$32.36$20.89 to $54.95

How much rates vary

Facilitymedian $32 · 10th to 90th $16 to $60Professionalmedian $20 · 10th to 90th $14 to $138
$20$50$100$200facility $32professional $20

Distribution of negotiated rates across all payers (price axis is log-scale). Each curve is scaled to its own total: facility and professional rates are different services, shown together to compare where they cluster. Need provider-level prices or 24+ months of history? Contact us.

Rates by insurance carrier

Insurance Carrier
Aetna
Setting
Facility
Modifier
Global
Typical Low
$15.85
Median
$48.98
Typical High
$60.26
Aetna
Setting
Professional
Modifier
Global
Typical Low
$13.80
Median
$15.85
Typical High
$138.04
Cigna
Setting
Professional
Modifier
Global
Typical Low
$25.70
Median
$39.81
Typical High
$50.12
Hally Health
Setting
Professional
Modifier
Global
Typical Low
$20.89
Median
$36.31
Typical High
$269.15
Medica
Setting
Facility
Modifier
Global
Typical Low
$20.89
Median
$26.92
Typical High
$64.57
Medica
Setting
Professional
Modifier
Global
Typical Low
$12.59
Median
$22.91
Typical High
$53.70
Midlands
Setting
Professional
Modifier
Global
Typical Low
$25.70
Median
$25.70
Typical High
$27.54
Midlands
Setting
Facility
Modifier
Global
Typical Low
$25.70
Median
$25.70
Typical High
$25.70
United
Setting
Facility
Modifier
Global
Typical Low
$20.89
Median
$20.89
Typical High
$45.71
United
Setting
Professional
Modifier
Global
Typical Low
$12.59
Median
$17.78
Typical High
$50.12
Wellmark
Setting
Professional
Modifier
Global
Typical Low
$16.60
Median
$20.89
Typical High
$20.89

Where Iowa sits

The same service costs 3.2 times more in Oklahoma than in Washington, DC. Every bar is a state, most expensive first. Touch or drag across it to read any state, then open that state for its carriers and full range.

Iowa· 14th of 51

$25.12

OK $50.12DC $15.49

Median negotiated rate in each state, from every insurer that publishes one. States where no insurer publishes a rate for this service are not shown.