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Complement Component Activity Test

Minnesota rates for HCPCS 86161

This blood test measures the functional activity of one specific protein within the complement system, a group of immune proteins that normally work together to fight infection and clear damaged cells. It is used to help investigate certain autoimmune diseases, recurrent infections, or unexplained inflammation. A low result can indicate that this particular protein is being used up faster than it can be replaced, or that a person was born with a shortage of it.

Rates data updated October 2026.

How much does Complement Component Activity Test cost?

$12.59

Typical negotiated rate. In Minnesota, October 2026.

Insurers have agreed to pay about $12.59 for this service. The price depends on where it is billed: about $12.02 from a physician practice, and about $25.70 from a hospital or other facility.

These are rates insurers have negotiated with providers, not the amount a patient is billed. What you owe depends on your plan's deductible and coinsurance. Based on rates published by 6 insurance carriers under federal price transparency rules.

Prices by location type

Billed byTypicalRange
Physician practiceA doctor's office, clinic or independent provider$12.02$10.23 to $14.45
FacilityA hospital or hospital-owned outpatient department$25.70$11.22 to $110

How much rates vary

Facilitymedian $26 · 10th to 90th $11 to $166Professionalmedian $12 · 10th to 90th $8 to $23
$10$20$50$100facility $26professional $12

Distribution of negotiated rates across all payers (price axis is log-scale). Need provider-level prices or 24+ months of history? Contact us.

Rates by insurance carrier

Insurance Carrier
Aetna
Setting
Facility
Modifier
None
Typical Low
$11.22
Median
$11.22
Typical High
$165.96
Aetna
Setting
Professional
Modifier
None
Typical Low
$10.96
Median
$11.22
Typical High
$20.89
BCBS Minnesota
Setting
Facility
Modifier
None
Typical Low
$11.48
Median
$12.02
Typical High
$91.20
BCBS Minnesota
Setting
Professional
Modifier
None
Typical Low
$9.55
Median
$10.72
Typical High
$12.02
Cigna
Setting
Facility
Modifier
None
Typical Low
$15.49
Median
$38.02
Typical High
$109.65
Cigna
Setting
Professional
Modifier
None
Typical Low
$13.80
Median
$17.38
Typical High
$22.91
Health Partners
Setting
Facility
Modifier
None
Typical Low
$22.39
Median
$37.15
Typical High
$87.10
Health Partners
Setting
Professional
Modifier
None
Typical Low
$13.49
Median
$13.49
Typical High
$22.91
Medica
Setting
Facility
Modifier
None
Typical Low
$12.02
Median
$23.44
Typical High
$141.25
Medica
Setting
Professional
Modifier
None
Typical Low
$6.92
Median
$12.02
Typical High
$31.62
United
Setting
Facility
Modifier
None
Typical Low
$12.02
Median
$12.02
Typical High
$14.45
United
Setting
Professional
Modifier
None
Typical Low
$5.01
Median
$10.96
Typical High
$28.18
4 more rates with less common billing modifiers

A modifier changes what was billed, for example a reduced or repeated service. Each of these modifiers carries under 10% of the published rates for this code. Modifier combinations, and modifiers with fewer than 30 rates for a carrier, are not listed.

Insurance Carrier
Aetna
Setting
Facility
Modifier
52 · Reduced service
Typical Low
$5.62
Median
$5.62
Typical High
$5.62
Aetna
Setting
Facility
Modifier
53 · Discontinued
Typical Low
$2.24
Median
$2.24
Typical High
$2.24
Aetna
Setting
Professional
Modifier
52 · Reduced service
Typical Low
$5.62
Median
$5.62
Typical High
$7.24
Aetna
Setting
Professional
Modifier
53 · Discontinued
Typical Low
$2.24
Median
$2.24
Typical High
$2.88

Where Minnesota sits

The same service costs 3.9 times more in Kansas than in Maryland. Every bar is a state, most expensive first. Touch or drag across it to read any state, then open that state for its carriers and full range.

Minnesota· 25th of 51

$12.59

KS $34.67MD $8.91

Median negotiated rate in each state, from every insurer that publishes one. States where no insurer publishes a rate for this service are not shown.