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Complement Component Activity Test

Massachusetts rates for HCPCS 86161

This blood test measures the functional activity of one specific protein within the complement system, a group of immune proteins that normally work together to fight infection and clear damaged cells. It is used to help investigate certain autoimmune diseases, recurrent infections, or unexplained inflammation. A low result can indicate that this particular protein is being used up faster than it can be replaced, or that a person was born with a shortage of it.

Rates data updated July 2026.

How much does Complement Component Activity Test cost?

$16.60

Typical negotiated rate. In Massachusetts, July 2026.

Insurers have agreed to pay about $16.60 for this service. The price depends on where it is billed: about $12.02 from a physician practice, and about $31.62 from a hospital or other facility. The two figures are alternatives, not parts of one bill.

These are rates insurers have negotiated with providers, not the amount a patient is billed. What you owe depends on your plan's deductible and coinsurance. Based on rates published by 9 insurance carriers under federal price transparency rules.

Where it's billed changes the price

Billed byTypicalRange
Physician practiceA doctor's office, clinic or independent provider$12.02$10.96 to $17.38
FacilityA hospital or hospital-owned outpatient department$31.62$20.89 to $53.70

How much rates vary

Facilitymedian $32 · 10th to 90th $12 to $93Professionalmedian $12 · 10th to 90th $10 to $38
$10$20$50$100$200facility $32professional $12

Distribution of negotiated rates across all payers (price axis is log-scale). Each curve is scaled to its own total: facility and professional rates are different services, shown together to compare where they cluster. Need provider-level prices or 24+ months of history? Contact us.

Rates by insurance carrier

Insurance Carrier
Aetna
Setting
Facility
Modifier
Global
Typical Low
$12.02
Median
$35.48
Typical High
$138.04
Aetna
Setting
Professional
Modifier
Global
Typical Low
$10.72
Median
$11.48
Typical High
$53.70
AllWays Health Partners
Setting
Facility
Modifier
Global
Typical Low
$10.96
Median
$16.98
Typical High
$141.25
AllWays Health Partners
Setting
Professional
Modifier
Global
Typical Low
$5.89
Median
$12.02
Typical High
$29.51
BCBS
Setting
Facility
Modifier
Global
Typical Low
$23.44
Median
$29.51
Typical High
$46.77
BCBS
Setting
Professional
Modifier
Global
Typical Low
$11.22
Median
$11.22
Typical High
$15.49
Cigna
Setting
Facility
Modifier
Global
Typical Low
$9.33
Median
$19.05
Typical High
$30.90
Cigna
Setting
Professional
Modifier
Global
Typical Low
$7.41
Median
$13.49
Typical High
$31.62
Fallon Health
Setting
Facility
Modifier
Global
Typical Low
$13.80
Median
$93.33
Typical High
$7,079.46
Fallon Health
Setting
Professional
Modifier
Global
Typical Low
$17.38
Median
$17.38
Typical High
$20.42
Harvard Pilgrim
Setting
Professional
Modifier
Global
Typical Low
$12.02
Median
$12.02
Typical High
$36.31
Health New England
Setting
Facility
Modifier
Global
Typical Low
$14.13
Median
$15.85
Typical High
$83.18
Mass General Brigham
Setting
Facility
Modifier
Global
Typical Low
$10.96
Median
$16.98
Typical High
$141.25
Mass General Brigham
Setting
Professional
Modifier
Global
Typical Low
$5.89
Median
$12.02
Typical High
$29.51
United
Setting
Facility
Modifier
Global
Typical Low
$6.92
Median
$12.02
Typical High
$17.38
United
Setting
Professional
Modifier
Global
Typical Low
$5.37
Median
$10.72
Typical High
$30.20

Where Massachusetts sits

The same service costs 2.9 times more in Pennsylvania than in Tennessee. Every bar is a state, most expensive first. Touch or drag across it to read any state, then open that state for its carriers and full range.

Massachusetts· 7th of 51

$16.60

PA $27.54TN $9.55

Median negotiated rate in each state, from every insurer that publishes one. States where no insurer publishes a rate for this service are not shown.