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Complement Component Activity Test

Alabama rates for HCPCS 86161

This blood test measures the functional activity of one specific protein within the complement system, a group of immune proteins that normally work together to fight infection and clear damaged cells. It is used to help investigate certain autoimmune diseases, recurrent infections, or unexplained inflammation. A low result can indicate that this particular protein is being used up faster than it can be replaced, or that a person was born with a shortage of it.

Rates data updated October 2026.

How much does Complement Component Activity Test cost?

$13.80

Typical negotiated rate. In Alabama, October 2026.

Insurers have agreed to pay about $13.80 for this service. The price depends on where it is billed: about $9.33 from a physician practice, and about $15.14 from a hospital or other facility.

These are rates insurers have negotiated with providers, not the amount a patient is billed. What you owe depends on your plan's deductible and coinsurance. Based on rates published by 5 insurance carriers under federal price transparency rules.

Prices by location type

Billed byTypicalRange
Physician practiceA doctor's office, clinic or independent provider$9.33$6.17 to $13.80
FacilityA hospital or hospital-owned outpatient department$15.14$15.14 to $15.14

How much rates vary

Facilitymedian $15 · 10th to 90th $14 to $15Professionalmedian $9 · 10th to 90th $5 to $14
$10$20$50facility $15professional $9

Distribution of negotiated rates across all payers (price axis is log-scale). Need provider-level prices or 24+ months of history? Contact us.

Rates by insurance carrier

Insurance Carrier
Aetna
Setting
Facility
Modifier
None
Typical Low
$13.18
Median
$13.80
Typical High
$18.62
Aetna
Setting
Professional
Modifier
None
Typical Low
$9.77
Median
$13.80
Typical High
$13.80
Ambetter
Setting
Professional
Modifier
None
Typical Low
$8.32
Median
$8.32
Typical High
$8.32
BCBS Alabama
Setting
Facility
Modifier
None
Typical Low
$15.14
Median
$15.14
Typical High
$15.14
BCBS Alabama
Setting
Professional
Modifier
21 + 22 · Increased work + 24 · Unrelated visit after surgery + 31 + 55 · Aftercare only + 99 · Multiple modifiers
Typical Low
$8.32
Median
$10.00
Typical High
$12.30
Cigna
Setting
Facility
Modifier
None
Typical Low
$9.77
Median
$10.23
Typical High
$38.02
Cigna
Setting
Professional
Modifier
None
Typical Low
$6.17
Median
$7.59
Typical High
$69.18
United
Setting
Facility
Modifier
None
Typical Low
$4.37
Median
$10.72
Typical High
$12.02
United
Setting
Professional
Modifier
None
Typical Low
$5.01
Median
$6.03
Typical High
$9.77
2 more rates with less common billing modifiers

A modifier changes what was billed, for example a reduced or repeated service. Each of these modifiers carries under 10% of the published rates for this code. Modifier combinations, and modifiers with fewer than 30 rates for a carrier, are not listed.

Insurance Carrier
Aetna
Setting
Professional
Modifier
52 · Reduced service
Typical Low
$5.37
Median
$6.92
Typical High
$6.92
Aetna
Setting
Professional
Modifier
53 · Discontinued
Typical Low
$2.14
Median
$2.75
Typical High
$2.75

Where Alabama sits

The same service costs 3.9 times more in Kansas than in Maryland. Every bar is a state, most expensive first. Touch or drag across it to read any state, then open that state for its carriers and full range.

Alabama· 16th of 51

$13.80

KS $34.67MD $8.91

Median negotiated rate in each state, from every insurer that publishes one. States where no insurer publishes a rate for this service are not shown.