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Clotting-regulation Protein Blood Test, Protein S

South Dakota rates for HCPCS 85306

This is a blood test that measures protein S, one of the body's natural proteins that helps keep blood clotting properly balanced. It's typically ordered as part of a work-up after an unexplained or recurrent blood clot, to check whether a deficiency in this protein might be a contributing factor. It's usually run together with a small set of related clot-regulation tests.

Rates data updated July 2026.

How much does Clotting-regulation Protein Blood Test, Protein S cost?

$39.81

Typical negotiated rate. In South Dakota, July 2026.

Insurers have agreed to pay about $39.81 for this service. The price depends on where it is billed: about $30.90 from a physician practice, and about $79.43 from a hospital or other facility. The two figures are alternatives, not parts of one bill.

These are rates insurers have negotiated with providers, not the amount a patient is billed. What you owe depends on your plan's deductible and coinsurance. Based on rates published by 7 insurance carriers under federal price transparency rules.

Where it's billed changes the price

Billed byTypicalRange
Physician practiceA doctor's office, clinic or independent provider$30.90$13.80 to $83.18
FacilityA hospital or hospital-owned outpatient department$79.43$64.57 to $117

How much rates vary

Facilitymedian $79 · 10th to 90th $29 to $240Professionalmedian $31 · 10th to 90th $12 to $138
$10$20$50$100$200facility $79professional $31

Distribution of negotiated rates across all payers (price axis is log-scale). Each curve is scaled to its own total: facility and professional rates are different services, shown together to compare where they cluster. Need provider-level prices or 24+ months of history? Contact us.

Rates by insurance carrier

Insurance Carrier
Aetna
Setting
Facility
Modifier
Global
Typical Low
$64.57
Median
$117.49
Typical High
$239.88
Aetna
Setting
Professional
Modifier
Global
Typical Low
$12.02
Median
$53.70
Typical High
$138.04
Avera
Setting
Facility
Modifier
Global
Typical Low
$14.13
Median
$15.49
Typical High
$22.91
Avera
Setting
Professional
Modifier
Global
Typical Low
$15.49
Median
$15.49
Typical High
$16.22
Cigna
Setting
Facility
Modifier
Global
Typical Low
$28.84
Median
$28.84
Typical High
$28.84
Cigna
Setting
Professional
Modifier
Global
Typical Low
$17.38
Median
$28.84
Typical High
$36.31
Medica
Setting
Facility
Modifier
Global
Typical Low
$14.45
Median
$23.44
Typical High
$95.50
Medica
Setting
Professional
Modifier
Global
Typical Low
$8.32
Median
$8.32
Typical High
$21.38
Sanford Health Plan
Setting
Professional
Modifier
Global
Typical Low
$21.88
Median
$32.36
Typical High
$41.69
United
Setting
Facility
Modifier
Global
Typical Low
$18.20
Median
$18.20
Typical High
$18.20
United
Setting
Professional
Modifier
Global
Typical Low
$6.46
Median
$13.80
Typical High
$21.38
Wellmark
Setting
Professional
Modifier
Global
Typical Low
$15.49
Median
$15.49
Typical High
$15.49

Where South Dakota sits

The same service costs 3.6 times more in West Virginia than in Kentucky. Every bar is a state, most expensive first. Touch or drag across it to read any state, then open that state for its carriers and full range.

South Dakota· 5th of 51

$39.81

WV $50.12KY $13.80

Median negotiated rate in each state, from every insurer that publishes one. States where no insurer publishes a rate for this service are not shown.