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Clotting-regulation Protein Blood Test, Protein S

Colorado rates for HCPCS 85306

This is a blood test that measures protein S, one of the body's natural proteins that helps keep blood clotting properly balanced. It's typically ordered as part of a work-up after an unexplained or recurrent blood clot, to check whether a deficiency in this protein might be a contributing factor. It's usually run together with a small set of related clot-regulation tests.

Rates data updated July 2026.

How much does Clotting-regulation Protein Blood Test, Protein S cost?

$15.49

Typical negotiated rate. In Colorado, July 2026.

Insurers have agreed to pay about $15.49 for this service. The price depends on where it is billed: about $12.30 from a physician practice, and about $52.48 from a hospital or other facility. The two figures are alternatives, not parts of one bill.

These are rates insurers have negotiated with providers, not the amount a patient is billed. What you owe depends on your plan's deductible and coinsurance. Based on rates published by 7 insurance carriers under federal price transparency rules.

Where it's billed changes the price

Billed byTypicalRange
Physician practiceA doctor's office, clinic or independent provider$12.30$11.75 to $13.80
FacilityA hospital or hospital-owned outpatient department$52.48$22.39 to $70.79

How much rates vary

Facilitymedian $52 · 10th to 90th $13 to $214Professionalmedian $12 · 10th to 90th $8 to $14
$10$20$50$100$200$500$1Kfacility $52professional $12

Distribution of negotiated rates across all payers (price axis is log-scale). Each curve is scaled to its own total: facility and professional rates are different services, shown together to compare where they cluster. Need provider-level prices or 24+ months of history? Contact us.

Rates by insurance carrier

Insurance Carrier
Aetna
Setting
Facility
Modifier
Global
Typical Low
$11.75
Median
$67.61
Typical High
$302.00
Aetna
Setting
Professional
Modifier
Global
Typical Low
$11.75
Median
$12.88
Typical High
$14.45
Anthem BCBS
Setting
Facility
Modifier
Global
Typical Low
$19.05
Median
$45.71
Typical High
$77.62
Anthem BCBS
Setting
Professional
Modifier
Global
Typical Low
$6.46
Median
$6.46
Typical High
$11.75
Cigna
Setting
Facility
Modifier
Global
Typical Low
$8.71
Median
$10.72
Typical High
$39.81
Cigna
Setting
Professional
Modifier
Global
Typical Low
$7.94
Median
$10.00
Typical High
$18.20
Denver HMP
Setting
Facility
Modifier
Global
Typical Low
$11.75
Median
$16.60
Typical High
$31.62
Kaiser Permanente
Setting
Professional
Modifier
Global
Typical Low
$21.88
Median
$263.03
Typical High
$263.03
Select Health
Setting
Facility
Modifier
Global
Typical Low
$16.22
Median
$28.18
Typical High
$32.36
Select Health
Setting
Professional
Modifier
Global
Typical Low
$10.72
Median
$10.72
Typical High
$15.49
United
Setting
Facility
Modifier
Global
Typical Low
$11.48
Median
$15.49
Typical High
$22.91
United
Setting
Professional
Modifier
Global
Typical Low
$6.46
Median
$8.91
Typical High
$14.45

Where Colorado sits

The same service costs 3.6 times more in West Virginia than in Kentucky. Every bar is a state, most expensive first. Touch or drag across it to read any state, then open that state for its carriers and full range.

Colorado· 37th of 51

$15.49

WV $50.12KY $13.80

Median negotiated rate in each state, from every insurer that publishes one. States where no insurer publishes a rate for this service are not shown.