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Free Estradiol Blood Test

North Carolina rates for HCPCS 82681

Measures the portion of estradiol, a main form of the hormone estrogen, that circulates unattached to carrier proteins in the blood. Only this unbound fraction is available to act on tissues, so it can give a clearer picture than a total measurement when carrier protein levels are unusual. It is a standard blood draw from a vein.

Rates data updated October 2026.

How much does Free Estradiol Blood Test cost?

$22.39

Typical negotiated rate. In North Carolina, October 2026.

Insurers have agreed to pay about $22.39 for this service. The price depends on where it is billed: about $18.20 from a physician practice, and about $23.99 from a hospital or other facility.

These are rates insurers have negotiated with providers, not the amount a patient is billed. What you owe depends on your plan's deductible and coinsurance. Based on rates published by 6 insurance carriers under federal price transparency rules.

Prices by location type

Billed byTypicalRange
Physician practiceA doctor's office, clinic or independent provider$18.20$14.13 to $25.12
FacilityA hospital or hospital-owned outpatient department$23.99$22.39 to $58.88

How much rates vary

Facilitymedian $24 · 10th to 90th $20 to $126Professionalmedian $18 · 10th to 90th $13 to $30
$20$50$100facility $24professional $18

Distribution of negotiated rates across all payers (price axis is log-scale). Need provider-level prices or 24+ months of history? Contact us.

Rates by insurance carrier

Insurance Carrier
Aetna
Setting
Facility
Modifier
None
Typical Low
$22.39
Median
$22.39
Typical High
$26.30
Aetna
Setting
Professional
Modifier
None
Typical Low
$19.50
Median
$22.39
Typical High
$25.70
Aetna
Setting
Professional
Modifier
52 · Reduced service
Typical Low
$11.22
Median
$11.22
Typical High
$11.22
Aetna
Setting
Professional
Modifier
53 · Discontinued
Typical Low
$4.47
Median
$4.47
Typical High
$4.47
BCBS North Carolina
Setting
Facility
Modifier
None
Typical Low
$58.88
Median
$61.66
Typical High
$89.13
BCBS North Carolina
Setting
Professional
Modifier
None
Typical Low
$12.59
Median
$12.59
Typical High
$18.20
Cigna
Setting
Facility
Modifier
None
Typical Low
$19.05
Median
$60.26
Typical High
$125.89
Cigna
Setting
Professional
Modifier
None
Typical Low
$12.88
Median
$14.13
Typical High
$36.31
Medcost
Setting
Professional
Modifier
None
Typical Low
$1,584.89
Median
$1,584.89
Typical High
$1,584.89
Medcost
Setting
Facility
Modifier
None
Typical Low
$18.20
Median
$22.39
Typical High
$28.18
Medcost
Setting
Professional
Modifier
None
Typical Low
$18.20
Median
$28.18
Typical High
$33.11
United
Setting
Professional
Modifier
None
Typical Low
$11.75
Median
$14.13
Typical High
$28.18
1 more rate with less common billing modifiers

A modifier changes what was billed, for example a reduced or repeated service. Each of these modifiers carries under 10% of the published rates for this code. Modifier combinations, and modifiers with fewer than 30 rates for a carrier, are not listed.

Insurance Carrier
Ambetter
Setting
Professional
Modifier
90 · Outside lab
Typical Low
$15.14
Median
$15.14
Typical High
$17.38

Where North Carolina sits

The same service costs 3.8 times more in Alaska than in Nebraska. Every bar is a state, most expensive first. Touch or drag across it to read any state, then open that state for its carriers and full range.

North Carolina· 33rd of 51

$22.39

AK $63.10NE $16.60

Median negotiated rate in each state, from every insurer that publishes one. States where no insurer publishes a rate for this service are not shown.