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Enzyme Activity Measurement

South Dakota rates for HCPCS 82658

A laboratory measurement of how much of a particular enzyme activity is present in blood cells, cultured cells or a piece of tissue. Enzymes are the proteins that carry out the body's chemical steps, and a level that is too low can explain an inherited condition affecting how the body processes certain substances. Each sample tested is reported separately.

Rates data updated July 2026.

Facilitymedian $83 · 10th–90th $43$830%50%10th$83Professionalmedian $49 · 10th–90th $30$1070%10%10th90th$49$20.0$50.0$100.0$200.0

Distribution of negotiated rates across all payers (price axis is log-scale). Facility and professional rates are different services and are charted separately. Need provider-level prices? Contact us.

Insurance Carrier
Aetna
Setting
Facility
Modifier
Global
Typical Low
$30.90
Median
$50.12
Typical High
$50.12
Aetna
Setting
Professional
Modifier
Global
Typical Low
$29.51
Median
$34.67
Typical High
$41.69
Cigna
Setting
Facility
Modifier
Global
Typical Low
$83.18
Median
$83.18
Typical High
$83.18
Cigna
Setting
Professional
Modifier
Global
Typical Low
$50.12
Median
$83.18
Typical High
$104.71
Medica
Setting
Facility
Modifier
Global
Typical Low
$27.54
Median
$50.12
Typical High
$81.28
Medica
Setting
Professional
Modifier
Global
Typical Low
$12.59
Median
$12.59
Typical High
$43.65
Sanford Health Plan
Setting
Professional
Modifier
Global
Typical Low
$43.65
Median
$91.20
Typical High
$120.23
United
Setting
Facility
Modifier
Global
Typical Low
$52.48
Median
$52.48
Typical High
$52.48
United
Setting
Professional
Modifier
Global
Typical Low
$12.59
Median
$26.30
Typical High
$50.12
Wellmark
Setting
Professional
Modifier
Global
Typical Low
$43.65
Median
$43.65
Typical High
$43.65