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Enzyme Activity Measurement

Massachusetts rates for HCPCS 82658

A laboratory measurement of how much of a particular enzyme activity is present in blood cells, cultured cells or a piece of tissue. Enzymes are the proteins that carry out the body's chemical steps, and a level that is too low can explain an inherited condition affecting how the body processes certain substances. Each sample tested is reported separately.

Rates data updated July 2026.

Facilitymedian $76 · 10th–90th $30$1290%10%10th90th$76Professionalmedian $44 · 10th–90th $17$810%20%40%10th90th$44$10.0$50.0$200.0$1.0K$5.0K$20.0K

Distribution of negotiated rates across all payers (price axis is log-scale). Facility and professional rates are different services and are charted separately. Need provider-level prices? Contact us.

Insurance Carrier
Aetna
Setting
Facility
Modifier
Global
Typical Low
$17.38
Median
$64.57
Typical High
$128.82
Aetna
Setting
Professional
Modifier
Global
Typical Low
$16.22
Median
$18.62
Typical High
$81.28
AllWays Health Partners
Setting
Facility
Modifier
Global
Typical Low
$32.36
Median
$50.12
Typical High
$208.93
AllWays Health Partners
Setting
Professional
Modifier
Global
Typical Low
$15.14
Median
$38.90
Typical High
$107.15
BCBS
Setting
Facility
Modifier
Global
Typical Low
$69.18
Median
$87.10
Typical High
$125.89
BCBS
Setting
Professional
Modifier
Global
Typical Low
$22.91
Median
$41.69
Typical High
$42.66
Cigna
Setting
Facility
Modifier
Global
Typical Low
$19.95
Median
$36.31
Typical High
$70.79
Cigna
Setting
Professional
Modifier
Global
Typical Low
$13.80
Median
$47.86
Typical High
$114.82
Fallon Health
Setting
Facility
Modifier
Global
Typical Low
$20.89
Median
$144.54
Typical High
$7,079.46
Fallon Health
Setting
Professional
Modifier
Global
Typical Low
$63.10
Median
$63.10
Typical High
$74.13
Harvard Pilgrim
Setting
Professional
Modifier
Global
Typical Low
$43.65
Median
$43.65
Typical High
$93.33
Mass General Brigham
Setting
Facility
Modifier
Global
Typical Low
$32.36
Median
$50.12
Typical High
$208.93
Mass General Brigham
Setting
Professional
Modifier
Global
Typical Low
$15.14
Median
$38.90
Typical High
$107.15
United
Setting
Facility
Modifier
Global
Typical Low
$15.14
Median
$30.90
Typical High
$43.65
United
Setting
Professional
Modifier
Global
Typical Low
$13.18
Median
$30.20
Typical High
$83.18