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Enzyme Activity Test, Blood or Tissue

Tennessee rates for HCPCS 82657

This is a laboratory test that measures how active a specific enzyme is in a blood, cell, or tissue sample, used when a more common, individually named enzyme test does not apply. It can help diagnose or monitor certain metabolic or inherited conditions where a particular enzyme is missing or not working properly.

Rates data updated July 2026.

How much does Enzyme Activity Test, Blood or Tissue cost?

$17.38

Typical negotiated rate. In Tennessee, July 2026.

Insurers have agreed to pay about $17.38 for this service. The price depends on where it is billed: about $16.60 from a physician practice, and about $35.48 from a hospital or other facility. The two figures are alternatives, not parts of one bill.

These are rates insurers have negotiated with providers, not the amount a patient is billed. What you owe depends on your plan's deductible and coinsurance. Based on rates published by 6 insurance carriers under federal price transparency rules.

Where it's billed changes the price

Billed byTypicalRange
Physician practiceA doctor's office, clinic or independent provider$16.60$16.60 to $19.95
FacilityA hospital or hospital-owned outpatient department$35.48$20.89 to $77.62

How much rates vary

Facilitymedian $35 · 10th to 90th $17 to $115Professionalmedian $17 · 10th to 90th $15 to $26
$5.0$20.0$100.0$500.0facility $35professional $17

Distribution of negotiated rates across all payers (price axis is log-scale). Each curve is scaled to its own total: facility and professional rates are different services, shown together to compare where they cluster. Need provider-level prices or 24+ months of history? Contact us.

Rates by insurance carrier

Insurance Carrier
Aetna
Setting
Facility
Modifier
Global
Typical Low
$17.38
Median
$35.48
Typical High
$114.82
Aetna
Setting
Professional
Modifier
Global
Typical Low
$16.60
Median
$16.60
Typical High
$25.70
Ambetter
Setting
Professional
Modifier
Global
Typical Low
$13.49
Median
$13.49
Typical High
$13.49
BCBS
Setting
Professional
Modifier
Global
Typical Low
$22.39
Median
$24.55
Typical High
$24.55
Cigna
Setting
Facility
Modifier
Global
Typical Low
$14.79
Median
$46.77
Typical High
$74.13
Cigna
Setting
Professional
Modifier
Global
Typical Low
$10.23
Median
$12.88
Typical High
$32.36
Lucent Health
Setting
Facility
Modifier
Global
Typical Low
$104.71
Median
$104.71
Typical High
$158.49
United
Setting
Facility
Modifier
Global
Typical Low
$8.91
Median
$19.95
Typical High
$22.39
United
Setting
Professional
Modifier
Global
Typical Low
$9.33
Median
$13.18
Typical High
$25.12

Where Tennessee sits

The same service costs 3.5 times more in Iowa than in Maryland. Every bar is a state, most expensive first. Pick one to see its carriers and full range.

Tennessee $17.38 · 50th of 51
IA $58.88MD $16.60

Median negotiated rate in each state, from every insurer that publishes one. States where no insurer publishes a rate for this service are not shown.