go back

Enzyme Activity Test, Blood or Tissue

South Carolina rates for HCPCS 82657

This is a laboratory test that measures how active a specific enzyme is in a blood, cell, or tissue sample, used when a more common, individually named enzyme test does not apply. It can help diagnose or monitor certain metabolic or inherited conditions where a particular enzyme is missing or not working properly.

Rates data updated July 2026.

How much does Enzyme Activity Test, Blood or Tissue cost?

$54.95

Typical negotiated rate. In South Carolina, July 2026.

Insurers have agreed to pay about $54.95 for this service. The price depends on where it is billed: about $17.78 from a physician practice, and about $91.20 from a hospital or other facility. The two figures are alternatives, not parts of one bill.

These are rates insurers have negotiated with providers, not the amount a patient is billed. What you owe depends on your plan's deductible and coinsurance. Based on rates published by 5 insurance carriers under federal price transparency rules.

Where it's billed changes the price

Billed byTypicalRange
Physician practiceA doctor's office, clinic or independent provider$17.78$17.38 to $21.88
FacilityA hospital or hospital-owned outpatient department$91.20$54.95 to $240

How much rates vary

Facilitymedian $91 · 10th to 90th $22 to $417Professionalmedian $18 · 10th to 90th $17 to $29
$10$20$50$100$200$500facility $91professional $18

Distribution of negotiated rates across all payers (price axis is log-scale). Each curve is scaled to its own total: facility and professional rates are different services, shown together to compare where they cluster. Need provider-level prices or 24+ months of history? Contact us.

Rates by insurance carrier

Insurance Carrier
Aetna
Setting
Facility
Modifier
Global
Typical Low
$30.90
Median
$95.50
Typical High
$416.87
Aetna
Setting
Professional
Modifier
Global
Typical Low
$17.38
Median
$17.38
Typical High
$23.44
BCBS
Setting
Facility
Modifier
Global
Typical Low
$31.62
Median
$77.62
Typical High
$676.08
BCBS
Setting
Professional
Modifier
Global
Typical Low
$19.95
Median
$23.44
Typical High
$36.31
Cigna
Setting
Facility
Modifier
Global
Typical Low
$41.69
Median
$72.44
Typical High
$147.91
Cigna
Setting
Professional
Modifier
Global
Typical Low
$10.23
Median
$11.75
Typical High
$28.84
Medcost
Setting
Facility
Modifier
Global
Typical Low
$16.60
Median
$23.44
Typical High
$38.02
United
Setting
Facility
Modifier
Global
Typical Low
$12.30
Median
$22.39
Typical High
$26.30
United
Setting
Professional
Modifier
Global
Typical Low
$9.33
Median
$13.18
Typical High
$26.30

Where South Carolina sits

The same service costs 3.5 times more in Iowa than in Maryland. Every bar is a state, most expensive first. Touch or drag across it to read any state, then open that state for its carriers and full range.

South Carolina· 2nd of 51

$54.95

IA $58.88MD $16.60

Median negotiated rate in each state, from every insurer that publishes one. States where no insurer publishes a rate for this service are not shown.