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Enzyme Activity Test, Blood or Tissue

Nebraska rates for HCPCS 82657

This is a laboratory test that measures how active a specific enzyme is in a blood, cell, or tissue sample, used when a more common, individually named enzyme test does not apply. It can help diagnose or monitor certain metabolic or inherited conditions where a particular enzyme is missing or not working properly.

Rates data updated July 2026.

How much does Enzyme Activity Test, Blood or Tissue cost?

$52.48

Typical negotiated rate. In Nebraska, July 2026.

Insurers have agreed to pay about $52.48 for this service. The price depends on where it is billed: about $16.22 from a physician practice, and about $74.13 from a hospital or other facility. The two figures are alternatives, not parts of one bill.

These are rates insurers have negotiated with providers, not the amount a patient is billed. What you owe depends on your plan's deductible and coinsurance. Based on rates published by 7 insurance carriers under federal price transparency rules.

Where it's billed changes the price

Billed byTypicalRange
Physician practiceA doctor's office, clinic or independent provider$16.22$14.79 to $44.67
FacilityA hospital or hospital-owned outpatient department$74.13$48.98 to $148

How much rates vary

Facilitymedian $74 · 10th to 90th $20 to $309Professionalmedian $16 · 10th to 90th $13 to $148
$10.0$20.0$50.0$100.0$200.0$500.0$1.0Kfacility $74professional $16

Distribution of negotiated rates across all payers (price axis is log-scale). Each curve is scaled to its own total: facility and professional rates are different services, shown together to compare where they cluster. Need provider-level prices or 24+ months of history? Contact us.

Rates by insurance carrier

Insurance Carrier
Aetna
Setting
Facility
Modifier
Global
Typical Low
$32.36
Median
$83.18
Typical High
$288.40
Aetna
Setting
Professional
Modifier
Global
Typical Low
$14.79
Median
$14.79
Typical High
$147.91
BCBS
Setting
Facility
Modifier
Global
Typical Low
$44.67
Median
$64.57
Typical High
$138.04
BCBS
Setting
Professional
Modifier
Global
Typical Low
$23.99
Median
$34.67
Typical High
$36.31
Cigna
Setting
Facility
Modifier
Global
Typical Low
$147.91
Median
$147.91
Typical High
$147.91
Cigna
Setting
Professional
Modifier
Global
Typical Low
$21.88
Median
$42.66
Typical High
$53.70
Medica
Setting
Facility
Modifier
Global
Typical Low
$13.18
Median
$35.48
Typical High
$288.40
Medica
Setting
Professional
Modifier
Global
Typical Low
$9.33
Median
$13.18
Typical High
$24.55
Midlands
Setting
Professional
Modifier
Global
Typical Low
$21.88
Median
$21.88
Typical High
$45.71
Midlands
Setting
Facility
Modifier
Global
Typical Low
$21.88
Median
$21.88
Typical High
$21.88
Oscar Health
Setting
Facility
Modifier
Global
Typical Low
$1,148.15
Median
$1,148.15
Typical High
$1,348.96
United
Setting
Facility
Modifier
Global
Typical Low
$9.33
Median
$19.95
Typical High
$22.39
United
Setting
Professional
Modifier
Global
Typical Low
$12.59
Median
$13.18
Typical High
$44.67

Where Nebraska sits

The same service costs 3.5 times more in Iowa than in Maryland. Every bar is a state, most expensive first. Pick one to see its carriers and full range.

Nebraska $52.48 · 3rd of 51
IA $58.88MD $16.60

Median negotiated rate in each state, from every insurer that publishes one. States where no insurer publishes a rate for this service are not shown.