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Enzyme Activity Test, Blood or Tissue

North Carolina rates for HCPCS 82657

This is a laboratory test that measures how active a specific enzyme is in a blood, cell, or tissue sample, used when a more common, individually named enzyme test does not apply. It can help diagnose or monitor certain metabolic or inherited conditions where a particular enzyme is missing or not working properly.

Rates data updated July 2026.

How much does Enzyme Activity Test, Blood or Tissue cost?

$32.36

Typical negotiated rate. In North Carolina, July 2026.

Insurers have agreed to pay about $32.36 for this service. The price depends on where it is billed: about $17.78 from a physician practice, and about $166 from a hospital or other facility. The two figures are alternatives, not parts of one bill.

These are rates insurers have negotiated with providers, not the amount a patient is billed. What you owe depends on your plan's deductible and coinsurance. Based on rates published by 8 insurance carriers under federal price transparency rules.

Where it's billed changes the price

Billed byTypicalRange
Physician practiceA doctor's office, clinic or independent provider$17.78$16.22 to $27.54
FacilityA hospital or hospital-owned outpatient department$166$33.11 to $363

How much rates vary

Facilitymedian $166 · 10th to 90th $18 to $513Professionalmedian $18 · 10th to 90th $13 to $55
$10.0$50.0$200.0$1.0Kfacility $166professional $18

Distribution of negotiated rates across all payers (price axis is log-scale). Each curve is scaled to its own total: facility and professional rates are different services, shown together to compare where they cluster. Need provider-level prices or 24+ months of history? Contact us.

Rates by insurance carrier

Insurance Carrier
Aetna
Setting
Facility
Modifier
Global
Typical Low
$18.62
Median
$169.82
Typical High
$512.86
Aetna
Setting
Professional
Modifier
Global
Typical Low
$16.22
Median
$17.78
Typical High
$64.57
Ambetter
Setting
Professional
Modifier
Global
Typical Low
$12.02
Median
$12.02
Typical High
$13.80
BCBS
Setting
Facility
Modifier
Global
Typical Low
$37.15
Median
$77.62
Typical High
$77.62
BCBS
Setting
Professional
Modifier
Global
Typical Low
$10.00
Median
$14.45
Typical High
$16.22
Cigna
Setting
Facility
Modifier
Global
Typical Low
$15.14
Median
$43.65
Typical High
$100.00
Cigna
Setting
Professional
Modifier
Global
Typical Low
$10.23
Median
$12.30
Typical High
$30.90
Medcost
Setting
Professional
Modifier
Global
Typical Low
$15.14
Median
$33.11
Typical High
$147.91
Medcost
Setting
Facility
Modifier
Global
Typical Low
$16.22
Median
$17.78
Typical High
$35.48
Medcost
Setting
Professional
Modifier
Global
Typical Low
$12.59
Median
$12.59
Typical High
$13.80
Oscar Health
Setting
Facility
Modifier
Global
Typical Low
$2,187.76
Median
$2,187.76
Typical High
$2,187.76
United
Setting
Facility
Modifier
Global
Typical Low
$10.96
Median
$25.12
Typical High
$31.62
United
Setting
Professional
Modifier
Global
Typical Low
$10.23
Median
$12.88
Typical High
$25.12
Wellcare
Setting
Facility
Modifier
Global
Typical Low
$104.71
Median
$104.71
Typical High
$158.49

Where North Carolina sits

The same service costs 3.5 times more in Iowa than in Maryland. Every bar is a state, most expensive first. Pick one to see its carriers and full range.

North Carolina $32.36 · 10th of 51
IA $58.88MD $16.60

Median negotiated rate in each state, from every insurer that publishes one. States where no insurer publishes a rate for this service are not shown.