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Enzyme Activity Test, Blood or Tissue

North Carolina rates for HCPCS 82657

This is a laboratory test that measures how active a specific enzyme is in a blood, cell, or tissue sample, used when a more common, individually named enzyme test does not apply. It can help diagnose or monitor certain metabolic or inherited conditions where a particular enzyme is missing or not working properly.

Rates data updated October 2026.

How much does Enzyme Activity Test, Blood or Tissue cost?

$17.78

Typical negotiated rate. In North Carolina, October 2026.

Insurers have agreed to pay about $17.78 for this service. The price depends on where it is billed: about $14.79 from a physician practice, and about $25.12 from a hospital or other facility.

These are rates insurers have negotiated with providers, not the amount a patient is billed. What you owe depends on your plan's deductible and coinsurance. Based on rates published by 6 insurance carriers under federal price transparency rules.

Prices by location type

Billed byTypicalRange
Physician practiceA doctor's office, clinic or independent provider$14.79$12.30 to $21.88
FacilityA hospital or hospital-owned outpatient department$25.12$17.78 to $47.86

How much rates vary

Facilitymedian $25 · 10th to 90th $17 to $100Professionalmedian $15 · 10th to 90th $11 to $26
$10$20$50$100facility $25professional $15

Distribution of negotiated rates across all payers (price axis is log-scale). Need provider-level prices or 24+ months of history? Contact us.

Rates by insurance carrier

Insurance Carrier
Aetna
Setting
Facility
Modifier
None
Typical Low
$17.78
Median
$18.20
Typical High
$45.71
Aetna
Setting
Professional
Modifier
None
Typical Low
$16.22
Median
$17.78
Typical High
$20.42
Aetna
Setting
Professional
Modifier
52 · Reduced service
Typical Low
$8.91
Median
$8.91
Typical High
$8.91
Aetna
Setting
Professional
Modifier
53 · Discontinued
Typical Low
$3.55
Median
$3.55
Typical High
$3.55
Ambetter
Setting
Professional
Modifier
None
Typical Low
$12.02
Median
$12.02
Typical High
$12.02
BCBS North Carolina
Setting
Facility
Modifier
None
Typical Low
$46.77
Median
$56.23
Typical High
$70.79
BCBS North Carolina
Setting
Professional
Modifier
None
Typical Low
$10.00
Median
$21.88
Typical High
$21.88
Cigna
Setting
Facility
Modifier
None
Typical Low
$15.14
Median
$48.98
Typical High
$100.00
Cigna
Setting
Professional
Modifier
None
Typical Low
$10.47
Median
$12.30
Typical High
$30.90
Medcost
Setting
Professional
Modifier
None
Typical Low
$15.14
Median
$33.11
Typical High
$147.91
Medcost
Setting
Facility
Modifier
None
Typical Low
$15.85
Median
$17.78
Typical High
$38.02
Medcost
Setting
Professional
Modifier
None
Typical Low
$12.59
Median
$25.70
Typical High
$37.15
United
Setting
Professional
Modifier
None
Typical Low
$9.33
Median
$12.88
Typical High
$24.55

Where North Carolina sits

The same service costs 5.0 times more in Alaska than in Georgia. Every bar is a state, most expensive first. Touch or drag across it to read any state, then open that state for its carriers and full range.

North Carolina· 42nd of 51

$17.78

AK $50.12GA $10.00

Median negotiated rate in each state, from every insurer that publishes one. States where no insurer publishes a rate for this service are not shown.