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Enzyme Activity Test, Blood or Tissue

Missouri rates for HCPCS 82657

This is a laboratory test that measures how active a specific enzyme is in a blood, cell, or tissue sample, used when a more common, individually named enzyme test does not apply. It can help diagnose or monitor certain metabolic or inherited conditions where a particular enzyme is missing or not working properly.

Rates data updated July 2026.

How much does Enzyme Activity Test, Blood or Tissue cost?

$28.84

Typical negotiated rate. In Missouri, July 2026.

Insurers have agreed to pay about $28.84 for this service. The price depends on where it is billed: about $21.38 from a physician practice, and about $38.02 from a hospital or other facility. The two figures are alternatives, not parts of one bill.

These are rates insurers have negotiated with providers, not the amount a patient is billed. What you owe depends on your plan's deductible and coinsurance. Based on rates published by 6 insurance carriers under federal price transparency rules.

Where it's billed changes the price

Billed byTypicalRange
Physician practiceA doctor's office, clinic or independent provider$21.38$18.62 to $31.62
FacilityA hospital or hospital-owned outpatient department$38.02$22.91 to $64.57

How much rates vary

Facilitymedian $38 · 10th to 90th $19 to $170Professionalmedian $21 · 10th to 90th $9 to $40
$10.0$20.0$50.0$100.0$200.0$500.0facility $38professional $21

Distribution of negotiated rates across all payers (price axis is log-scale). Each curve is scaled to its own total: facility and professional rates are different services, shown together to compare where they cluster. Need provider-level prices or 24+ months of history? Contact us.

Rates by insurance carrier

Insurance Carrier
Aetna
Setting
Facility
Modifier
Global
Typical Low
$19.05
Median
$38.90
Typical High
$169.82
Aetna
Setting
Professional
Modifier
Global
Typical Low
$19.05
Median
$25.70
Typical High
$37.15
Anthem BCBS
Setting
Facility
Modifier
Global
Typical Low
$22.39
Median
$22.39
Typical High
$77.62
Anthem BCBS
Setting
Professional
Modifier
Global
Typical Low
$8.91
Median
$16.98
Typical High
$51.29
BCBS
Setting
Facility
Modifier
Global
Typical Low
$16.60
Median
$17.78
Typical High
$38.02
Cigna
Setting
Facility
Modifier
Global
Typical Low
$23.99
Median
$42.66
Typical High
$102.33
Cigna
Setting
Professional
Modifier
Global
Typical Low
$10.47
Median
$20.89
Typical High
$46.77
Medica
Setting
Facility
Modifier
Global
Typical Low
$19.50
Median
$34.67
Typical High
$158.49
Medica
Setting
Professional
Modifier
Global
Typical Low
$9.33
Median
$13.18
Typical High
$23.99
United
Setting
Facility
Modifier
Global
Typical Low
$10.23
Median
$22.39
Typical High
$26.30
United
Setting
Professional
Modifier
Global
Typical Low
$9.33
Median
$13.18
Typical High
$26.30

Where Missouri sits

The same service costs 3.5 times more in Iowa than in Maryland. Every bar is a state, most expensive first. Pick one to see its carriers and full range.

Missouri $28.84 · 15th of 51
IA $58.88MD $16.60

Median negotiated rate in each state, from every insurer that publishes one. States where no insurer publishes a rate for this service are not shown.