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Enzyme Activity Test, Blood or Tissue

Minnesota rates for HCPCS 82657

This is a laboratory test that measures how active a specific enzyme is in a blood, cell, or tissue sample, used when a more common, individually named enzyme test does not apply. It can help diagnose or monitor certain metabolic or inherited conditions where a particular enzyme is missing or not working properly.

Rates data updated October 2026.

How much does Enzyme Activity Test, Blood or Tissue cost?

$25.70

Typical negotiated rate. In Minnesota, October 2026.

Insurers have agreed to pay about $25.70 for this service. The price depends on where it is billed: about $22.39 from a physician practice, and about $69.18 from a hospital or other facility.

These are rates insurers have negotiated with providers, not the amount a patient is billed. What you owe depends on your plan's deductible and coinsurance. Based on rates published by 6 insurance carriers under federal price transparency rules.

Prices by location type

Billed byTypicalRange
Physician practiceA doctor's office, clinic or independent provider$22.39$17.78 to $26.92
FacilityA hospital or hospital-owned outpatient department$69.18$22.39 to $158

How much rates vary

Facilitymedian $69 · 10th to 90th $21 to $4,677Professionalmedian $22 · 10th to 90th $13 to $43
$10$50$200$1K$5Kfacility $69professional $22

Distribution of negotiated rates across all payers (price axis is log-scale). Need provider-level prices or 24+ months of history? Contact us.

Rates by insurance carrier

Insurance Carrier
Aetna
Setting
Facility
Modifier
None
Typical Low
$20.89
Median
$147.91
Typical High
$4,677.35
Aetna
Setting
Professional
Modifier
None
Typical Low
$17.78
Median
$20.89
Typical High
$26.92
BCBS Minnesota
Setting
Facility
Modifier
None
Typical Low
$20.89
Median
$22.39
Typical High
$89.13
BCBS Minnesota
Setting
Professional
Modifier
None
Typical Low
$17.78
Median
$19.95
Typical High
$22.39
Cigna
Setting
Facility
Modifier
None
Typical Low
$26.92
Median
$70.79
Typical High
$208.93
Cigna
Setting
Professional
Modifier
None
Typical Low
$25.70
Median
$32.36
Typical High
$42.66
Health Partners
Setting
Facility
Modifier
None
Typical Low
$41.69
Median
$69.18
Typical High
$162.18
Health Partners
Setting
Professional
Modifier
None
Typical Low
$25.70
Median
$25.70
Typical High
$42.66
Medica
Setting
Facility
Modifier
None
Typical Low
$26.92
Median
$54.95
Typical High
$218.78
Medica
Setting
Professional
Modifier
None
Typical Low
$12.30
Median
$22.39
Typical High
$58.88
United
Setting
Facility
Modifier
None
Typical Low
$22.39
Median
$22.39
Typical High
$26.30
United
Setting
Professional
Modifier
None
Typical Low
$9.33
Median
$20.42
Typical High
$52.48
4 more rates with less common billing modifiers

A modifier changes what was billed, for example a reduced or repeated service. Each of these modifiers carries under 10% of the published rates for this code. Modifier combinations, and modifiers with fewer than 30 rates for a carrier, are not listed.

Insurance Carrier
Aetna
Setting
Facility
Modifier
52 · Reduced service
Typical Low
$10.47
Median
$10.47
Typical High
$10.47
Aetna
Setting
Facility
Modifier
53 · Discontinued
Typical Low
$4.17
Median
$4.17
Typical High
$4.17
Aetna
Setting
Professional
Modifier
52 · Reduced service
Typical Low
$10.47
Median
$10.47
Typical High
$13.18
Aetna
Setting
Professional
Modifier
53 · Discontinued
Typical Low
$4.17
Median
$4.17
Typical High
$5.37

Where Minnesota sits

The same service costs 5.0 times more in Alaska than in Georgia. Every bar is a state, most expensive first. Touch or drag across it to read any state, then open that state for its carriers and full range.

Minnesota· 13th of 51

$25.70

AK $50.12GA $10.00

Median negotiated rate in each state, from every insurer that publishes one. States where no insurer publishes a rate for this service are not shown.