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Enzyme Activity Test, Blood or Tissue

Minnesota rates for HCPCS 82657

This is a laboratory test that measures how active a specific enzyme is in a blood, cell, or tissue sample, used when a more common, individually named enzyme test does not apply. It can help diagnose or monitor certain metabolic or inherited conditions where a particular enzyme is missing or not working properly.

Rates data updated July 2026.

How much does Enzyme Activity Test, Blood or Tissue cost?

$22.39

Typical negotiated rate. In Minnesota, July 2026.

Insurers have agreed to pay about $22.39 for this service. The price depends on where it is billed: about $22.39 from a physician practice, and about $64.57 from a hospital or other facility. The two figures are alternatives, not parts of one bill.

These are rates insurers have negotiated with providers, not the amount a patient is billed. What you owe depends on your plan's deductible and coinsurance. Based on rates published by 6 insurance carriers under federal price transparency rules.

Where it's billed changes the price

Billed byTypicalRange
Physician practiceA doctor's office, clinic or independent provider$22.39$20.89 to $25.70
FacilityA hospital or hospital-owned outpatient department$64.57$22.39 to $162

How much rates vary

Facilitymedian $65 · 10th to 90th $22 to $195Professionalmedian $22 · 10th to 90th $18 to $39
$10.0$20.0$50.0$100.0$200.0$500.0facility $65professional $22

Distribution of negotiated rates across all payers (price axis is log-scale). Each curve is scaled to its own total: facility and professional rates are different services, shown together to compare where they cluster. Need provider-level prices or 24+ months of history? Contact us.

Rates by insurance carrier

Insurance Carrier
Aetna
Setting
Facility
Modifier
Global
Typical Low
$20.89
Median
$181.97
Typical High
$398.11
Aetna
Setting
Professional
Modifier
Global
Typical Low
$16.22
Median
$20.89
Typical High
$177.83
BCBS
Setting
Facility
Modifier
Global
Typical Low
$22.39
Median
$22.39
Typical High
$67.61
BCBS
Setting
Professional
Modifier
Global
Typical Low
$17.78
Median
$22.39
Typical High
$22.39
Cigna
Setting
Facility
Modifier
Global
Typical Low
$42.66
Median
$75.86
Typical High
$208.93
Cigna
Setting
Professional
Modifier
Global
Typical Low
$25.70
Median
$32.36
Typical High
$43.65
Health Partners
Setting
Facility
Modifier
Global
Typical Low
$48.98
Median
$70.79
Typical High
$162.18
Health Partners
Setting
Professional
Modifier
Global
Typical Low
$25.70
Median
$25.70
Typical High
$42.66
Medica
Setting
Facility
Modifier
Global
Typical Low
$26.30
Median
$58.88
Typical High
$257.04
Medica
Setting
Professional
Modifier
Global
Typical Low
$10.96
Median
$15.14
Typical High
$131.83
United
Setting
Facility
Modifier
Global
Typical Low
$13.49
Median
$26.30
Typical High
$63.10
United
Setting
Professional
Modifier
Global
Typical Low
$10.96
Median
$22.39
Typical High
$48.98

Where Minnesota sits

The same service costs 3.5 times more in Iowa than in Maryland. Every bar is a state, most expensive first. Pick one to see its carriers and full range.

Minnesota $22.39 · 34th of 51
IA $58.88MD $16.60

Median negotiated rate in each state, from every insurer that publishes one. States where no insurer publishes a rate for this service are not shown.