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Enzyme Activity Test, Blood or Tissue

Michigan rates for HCPCS 82657

This is a laboratory test that measures how active a specific enzyme is in a blood, cell, or tissue sample, used when a more common, individually named enzyme test does not apply. It can help diagnose or monitor certain metabolic or inherited conditions where a particular enzyme is missing or not working properly.

Rates data updated October 2026.

How much does Enzyme Activity Test, Blood or Tissue cost?

$19.05

Typical negotiated rate. In Michigan, October 2026.

Insurers have agreed to pay about $19.05 for this service. The price depends on where it is billed: about $16.60 from a physician practice, and about $21.38 from a hospital or other facility.

These are rates insurers have negotiated with providers, not the amount a patient is billed. What you owe depends on your plan's deductible and coinsurance. Based on rates published by 6 insurance carriers under federal price transparency rules.

Prices by location type

Billed byTypicalRange
Physician practiceA doctor's office, clinic or independent provider$16.60$15.49 to $21.38
FacilityA hospital or hospital-owned outpatient department$21.38$20.89 to $33.11

How much rates vary

Facilitymedian $21 · 10th to 90th $17 to $42Professionalmedian $17 · 10th to 90th $10 to $24
$10$20$50$100facility $21professional $17

Distribution of negotiated rates across all payers (price axis is log-scale). Need provider-level prices or 24+ months of history? Contact us.

Rates by insurance carrier

Insurance Carrier
Aetna
Setting
Facility
Modifier
None
Typical Low
$20.89
Median
$20.89
Typical High
$33.11
Aetna
Setting
Facility
Modifier
52 · Reduced service
Typical Low
$10.47
Median
$10.47
Typical High
$16.60
Aetna
Setting
Facility
Modifier
53 · Discontinued
Typical Low
$4.17
Median
$4.17
Typical High
$6.61
Aetna
Setting
Professional
Modifier
None
Typical Low
$19.05
Median
$21.38
Typical High
$26.30
Aetna
Setting
Professional
Modifier
52 · Reduced service
Typical Low
$9.33
Median
$10.72
Typical High
$11.22
Aetna
Setting
Professional
Modifier
53 · Discontinued
Typical Low
$3.80
Median
$4.27
Typical High
$4.47
BCBS Michigan
Setting
Facility
Modifier
None
Typical Low
$16.60
Median
$23.44
Typical High
$41.69
BCBS Michigan
Setting
Professional
Modifier
None
Typical Low
$16.60
Median
$16.60
Typical High
$16.60
Cigna
Setting
Professional
Modifier
None
Typical Low
$11.22
Median
$13.80
Typical High
$32.36
Health Alliance Plan
Setting
Facility
Modifier
None
Typical Low
$20.89
Median
$26.30
Typical High
$45.71
Health Alliance Plan
Setting
Facility
Modifier
52 · Reduced service
Typical Low
$10.47
Median
$10.47
Typical High
$16.60
Health Alliance Plan
Setting
Facility
Modifier
53 · Discontinued
Typical Low
$4.17
Median
$4.17
Typical High
$6.61
Health Alliance Plan
Setting
Professional
Modifier
None
Typical Low
$15.49
Median
$20.89
Typical High
$26.30
Health Alliance Plan
Setting
Professional
Modifier
52 · Reduced service
Typical Low
$10.47
Median
$10.47
Typical High
$10.47
Health Alliance Plan
Setting
Professional
Modifier
53 · Discontinued
Typical Low
$4.17
Median
$4.17
Typical High
$4.17
Priority Health
Setting
Professional
Modifier
None
Typical Low
$11.48
Median
$14.13
Typical High
$25.70
United
Setting
Facility
Modifier
None
Typical Low
$13.18
Median
$19.95
Typical High
$26.30
United
Setting
Professional
Modifier
None
Typical Low
$7.08
Median
$9.77
Typical High
$25.12

Where Michigan sits

The same service costs 5.0 times more in Alaska than in Georgia. Every bar is a state, most expensive first. Touch or drag across it to read any state, then open that state for its carriers and full range.

Michigan· 31st of 51

$19.05

AK $50.12GA $10.00

Median negotiated rate in each state, from every insurer that publishes one. States where no insurer publishes a rate for this service are not shown.