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Enzyme Activity Test, Blood or Tissue

Maine rates for HCPCS 82657

This is a laboratory test that measures how active a specific enzyme is in a blood, cell, or tissue sample, used when a more common, individually named enzyme test does not apply. It can help diagnose or monitor certain metabolic or inherited conditions where a particular enzyme is missing or not working properly.

Rates data updated July 2026.

How much does Enzyme Activity Test, Blood or Tissue cost?

$22.39

Typical negotiated rate. In Maine, July 2026.

Insurers have agreed to pay about $22.39 for this service. The price depends on where it is billed: about $22.39 from a physician practice, and about $57.54 from a hospital or other facility. The two figures are alternatives, not parts of one bill.

These are rates insurers have negotiated with providers, not the amount a patient is billed. What you owe depends on your plan's deductible and coinsurance. Based on rates published by 6 insurance carriers under federal price transparency rules.

Where it's billed changes the price

Billed byTypicalRange
Physician practiceA doctor's office, clinic or independent provider$22.39$16.98 to $22.39
FacilityA hospital or hospital-owned outpatient department$57.54$22.39 to $170

How much rates vary

Facilitymedian $58 · 10th to 90th $22 to $427Professionalmedian $22 · 10th to 90th $13 to $26
$10.0$50.0$200.0$1.0Kfacility $58professional $22

Distribution of negotiated rates across all payers (price axis is log-scale). Each curve is scaled to its own total: facility and professional rates are different services, shown together to compare where they cluster. Need provider-level prices or 24+ months of history? Contact us.

Rates by insurance carrier

Insurance Carrier
Aetna
Setting
Facility
Modifier
Global
Typical Low
$22.39
Median
$54.95
Typical High
$1,202.26
Aetna
Setting
Professional
Modifier
Global
Typical Low
$16.98
Median
$17.78
Typical High
$22.39
Anthem BCBS
Setting
Facility
Modifier
Global
Typical Low
$25.70
Median
$169.82
Typical High
$181.97
Anthem BCBS
Setting
Professional
Modifier
Global
Typical Low
$8.91
Median
$12.59
Typical High
$23.44
Cigna
Setting
Facility
Modifier
Global
Typical Low
$21.38
Median
$25.12
Typical High
$50.12
Cigna
Setting
Professional
Modifier
Global
Typical Low
$18.20
Median
$22.39
Typical High
$26.30
Harvard Pilgrim
Setting
Professional
Modifier
Global
Typical Low
$14.79
Median
$22.39
Typical High
$26.92
Martin's Point
Setting
Facility
Modifier
Global
Typical Low
$22.39
Median
$54.95
Typical High
$776.25
Martin's Point
Setting
Professional
Modifier
Global
Typical Low
$17.78
Median
$22.39
Typical High
$23.44
United
Setting
Facility
Modifier
Global
Typical Low
$63.10
Median
$63.10
Typical High
$63.10
United
Setting
Professional
Modifier
Global
Typical Low
$13.18
Median
$22.39
Typical High
$37.15

Where Maine sits

The same service costs 3.5 times more in Iowa than in Maryland. Every bar is a state, most expensive first. Pick one to see its carriers and full range.

Maine $22.39 · 36th of 51
IA $58.88MD $16.60

Median negotiated rate in each state, from every insurer that publishes one. States where no insurer publishes a rate for this service are not shown.