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Enzyme Activity Test, Blood or Tissue

Kentucky rates for HCPCS 82657

This is a laboratory test that measures how active a specific enzyme is in a blood, cell, or tissue sample, used when a more common, individually named enzyme test does not apply. It can help diagnose or monitor certain metabolic or inherited conditions where a particular enzyme is missing or not working properly.

Rates data updated October 2026.

How much does Enzyme Activity Test, Blood or Tissue cost?

$15.49

Typical negotiated rate. In Kentucky, October 2026.

Insurers have agreed to pay about $15.49 for this service. The price depends on where it is billed: about $15.49 from a physician practice, and about $22.39 from a hospital or other facility.

These are rates insurers have negotiated with providers, not the amount a patient is billed. What you owe depends on your plan's deductible and coinsurance. Based on rates published by 5 insurance carriers under federal price transparency rules.

Prices by location type

Billed byTypicalRange
Physician practiceA doctor's office, clinic or independent provider$15.49$10.00 to $22.39
FacilityA hospital or hospital-owned outpatient department$22.39$17.78 to $33.11

How much rates vary

Facilitymedian $22 · 10th to 90th $14 to $33Professionalmedian $15 · 10th to 90th $9 to $25
$10$20$50$100facility $22professional $15

Distribution of negotiated rates across all payers (price axis is log-scale). Need provider-level prices or 24+ months of history? Contact us.

Rates by insurance carrier

Insurance Carrier
Aetna
Setting
Facility
Modifier
None
Typical Low
$8.32
Median
$18.62
Typical High
$41.69
Aetna
Setting
Professional
Modifier
None
Typical Low
$8.32
Median
$17.78
Typical High
$22.39
Anthem BCBS
Setting
Facility
Modifier
None
Typical Low
$13.80
Median
$22.39
Typical High
$23.44
Anthem BCBS
Setting
Professional
Modifier
None
Typical Low
$8.91
Median
$15.49
Typical High
$25.12
CareSource
Setting
Facility
Modifier
None
Typical Low
$22.39
Median
$26.30
Typical High
$30.90
CareSource
Setting
Professional
Modifier
None
Typical Low
$22.39
Median
$27.54
Typical High
$44.67
Cigna
Setting
Facility
Modifier
None
Typical Low
$17.38
Median
$33.11
Typical High
$46.77
Cigna
Setting
Professional
Modifier
None
Typical Low
$10.23
Median
$120.23
Typical High
$120.23
United
Setting
Professional
Modifier
None
Typical Low
$9.33
Median
$15.14
Typical High
$25.12
2 more rates with less common billing modifiers

A modifier changes what was billed, for example a reduced or repeated service. Each of these modifiers carries under 10% of the published rates for this code. Modifier combinations, and modifiers with fewer than 30 rates for a carrier, are not listed.

Insurance Carrier
Aetna
Setting
Professional
Modifier
52 · Reduced service
Typical Low
$4.17
Median
$9.33
Typical High
$10.96
Aetna
Setting
Professional
Modifier
53 · Discontinued
Typical Low
$1.66
Median
$3.72
Typical High
$4.47

Where Kentucky sits

The same service costs 5.0 times more in Alaska than in Georgia. Every bar is a state, most expensive first. Touch or drag across it to read any state, then open that state for its carriers and full range.

Kentucky· 50th of 51

$15.49

AK $50.12GA $10.00

Median negotiated rate in each state, from every insurer that publishes one. States where no insurer publishes a rate for this service are not shown.