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Enzyme Activity Test, Blood or Tissue

Illinois rates for HCPCS 82657

This is a laboratory test that measures how active a specific enzyme is in a blood, cell, or tissue sample, used when a more common, individually named enzyme test does not apply. It can help diagnose or monitor certain metabolic or inherited conditions where a particular enzyme is missing or not working properly.

Rates data updated July 2026.

How much does Enzyme Activity Test, Blood or Tissue cost?

$26.30

Typical negotiated rate. In Illinois, July 2026.

Insurers have agreed to pay about $26.30 for this service. The price depends on where it is billed: about $17.38 from a physician practice, and about $45.71 from a hospital or other facility. The two figures are alternatives, not parts of one bill.

These are rates insurers have negotiated with providers, not the amount a patient is billed. What you owe depends on your plan's deductible and coinsurance. Based on rates published by 6 insurance carriers under federal price transparency rules.

Where it's billed changes the price

Billed byTypicalRange
Physician practiceA doctor's office, clinic or independent provider$17.38$15.14 to $22.91
FacilityA hospital or hospital-owned outpatient department$45.71$32.36 to $148

How much rates vary

Facilitymedian $46 · 10th to 90th $22 to $603Professionalmedian $17 · 10th to 90th $3 to $45
$5.0$20.0$100.0$500.0facility $46professional $17

Distribution of negotiated rates across all payers (price axis is log-scale). Each curve is scaled to its own total: facility and professional rates are different services, shown together to compare where they cluster. Need provider-level prices or 24+ months of history? Contact us.

Rates by insurance carrier

Insurance Carrier
Aetna
Setting
Facility
Modifier
Global
Typical Low
$22.39
Median
$45.71
Typical High
$602.56
Aetna
Setting
Professional
Modifier
Global
Typical Low
$16.22
Median
$19.05
Typical High
$45.71
BCBS
Setting
Facility
Modifier
Global
Typical Low
$27.54
Median
$50.12
Typical High
$208.93
BCBS
Setting
Professional
Modifier
Global
Typical Low
$3.47
Median
$15.14
Typical High
$16.98
Cigna
Setting
Facility
Modifier
Global
Typical Low
$21.38
Median
$45.71
Typical High
$102.33
Cigna
Setting
Professional
Modifier
Global
Typical Low
$11.22
Median
$23.99
Typical High
$38.02
Hally Health
Setting
Professional
Modifier
Global
Typical Low
$24.55
Median
$38.90
Typical High
$199.53
Hally Health
Setting
Facility
Modifier
Global
Typical Low
$100.00
Median
$100.00
Typical High
$100.00
Hally Health
Setting
Professional
Modifier
Global
Typical Low
$28.84
Median
$28.84
Typical High
$28.84
Molina
Setting
Professional
Modifier
Global
Typical Low
$12.30
Median
$12.30
Typical High
$15.49
United
Setting
Facility
Modifier
Global
Typical Low
$12.59
Median
$22.39
Typical High
$44.67
United
Setting
Professional
Modifier
Global
Typical Low
$9.33
Median
$13.49
Typical High
$22.39

Where Illinois sits

The same service costs 3.5 times more in Iowa than in Maryland. Every bar is a state, most expensive first. Pick one to see its carriers and full range.

Illinois $26.30 · 20th of 51
IA $58.88MD $16.60

Median negotiated rate in each state, from every insurer that publishes one. States where no insurer publishes a rate for this service are not shown.