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Enzyme Activity Test, Blood or Tissue

Iowa rates for HCPCS 82657

This is a laboratory test that measures how active a specific enzyme is in a blood, cell, or tissue sample, used when a more common, individually named enzyme test does not apply. It can help diagnose or monitor certain metabolic or inherited conditions where a particular enzyme is missing or not working properly.

Rates data updated July 2026.

How much does Enzyme Activity Test, Blood or Tissue cost?

$58.88

Typical negotiated rate. In Iowa, July 2026.

Insurers have agreed to pay about $58.88 for this service. The price depends on where it is billed: about $42.66 from a physician practice, and about $83.18 from a hospital or other facility. The two figures are alternatives, not parts of one bill.

These are rates insurers have negotiated with providers, not the amount a patient is billed. What you owe depends on your plan's deductible and coinsurance. Based on rates published by 8 insurance carriers under federal price transparency rules.

Where it's billed changes the price

Billed byTypicalRange
Physician practiceA doctor's office, clinic or independent provider$42.66$16.98 to $138
FacilityA hospital or hospital-owned outpatient department$83.18$34.67 to $263

How much rates vary

Facilitymedian $83 · 10th to 90th $22 to $1,259Professionalmedian $43 · 10th to 90th $15 to $151
$10.0$50.0$200.0$1.0Kfacility $83professional $43

Distribution of negotiated rates across all payers (price axis is log-scale). Each curve is scaled to its own total: facility and professional rates are different services, shown together to compare where they cluster. Need provider-level prices or 24+ months of history? Contact us.

Rates by insurance carrier

Insurance Carrier
Aetna
Setting
Facility
Modifier
Global
Typical Low
$22.39
Median
$61.66
Typical High
$302.00
Aetna
Setting
Professional
Modifier
Global
Typical Low
$16.98
Median
$134.90
Typical High
$151.36
Cigna
Setting
Professional
Modifier
Global
Typical Low
$26.92
Median
$42.66
Typical High
$53.70
Hally Health
Setting
Professional
Modifier
Global
Typical Low
$22.39
Median
$39.81
Typical High
$107.15
Medica
Setting
Facility
Modifier
Global
Typical Low
$22.39
Median
$28.84
Typical High
$64.57
Medica
Setting
Professional
Modifier
Global
Typical Low
$13.18
Median
$22.39
Typical High
$51.29
Midlands
Setting
Professional
Modifier
Global
Typical Low
$21.88
Median
$27.54
Typical High
$29.51
Midlands
Setting
Facility
Modifier
Global
Typical Low
$21.88
Median
$21.88
Typical High
$21.88
Oscar Health
Setting
Facility
Modifier
Global
Typical Low
$257.04
Median
$288.40
Typical High
$2,041.74
United
Setting
Facility
Modifier
Global
Typical Low
$22.39
Median
$22.39
Typical High
$51.29
United
Setting
Professional
Modifier
Global
Typical Low
$13.18
Median
$15.14
Typical High
$51.29
Wellmark
Setting
Professional
Modifier
Global
Typical Low
$17.38
Median
$22.39
Typical High
$22.39

Where Iowa sits

The same service costs 3.5 times more in Iowa than in Maryland. Every bar is a state, most expensive first. Pick one to see its carriers and full range.

Iowa $58.88 · 1st of 51
IA $58.88MD $16.60

Median negotiated rate in each state, from every insurer that publishes one. States where no insurer publishes a rate for this service are not shown.