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Enzyme Activity Test, Blood or Tissue

Iowa rates for HCPCS 82657

This is a laboratory test that measures how active a specific enzyme is in a blood, cell, or tissue sample, used when a more common, individually named enzyme test does not apply. It can help diagnose or monitor certain metabolic or inherited conditions where a particular enzyme is missing or not working properly.

Rates data updated October 2026.

How much does Enzyme Activity Test, Blood or Tissue cost?

$26.30

Typical negotiated rate. In Iowa, October 2026.

Insurers have agreed to pay about $26.30 for this service. The price depends on where it is billed: about $22.39 from a physician practice, and about $32.36 from a hospital or other facility.

These are rates insurers have negotiated with providers, not the amount a patient is billed. What you owe depends on your plan's deductible and coinsurance. Based on rates published by 7 insurance carriers under federal price transparency rules.

Prices by location type

Billed byTypicalRange
Physician practiceA doctor's office, clinic or independent provider$22.39$15.49 to $39.81
FacilityA hospital or hospital-owned outpatient department$32.36$26.92 to $52.48

How much rates vary

Facilitymedian $32 · 10th to 90th $22 to $65Professionalmedian $22 · 10th to 90th $13 to $52
$10$20$50$100facility $32professional $22

Distribution of negotiated rates across all payers (price axis is log-scale). Need provider-level prices or 24+ months of history? Contact us.

Rates by insurance carrier

Insurance Carrier
Aetna
Setting
Facility
Modifier
None
Typical Low
$17.38
Median
$33.88
Typical High
$63.10
Aetna
Setting
Professional
Modifier
None
Typical Low
$14.79
Median
$17.38
Typical High
$26.30
Cigna
Setting
Professional
Modifier
None
Typical Low
$23.99
Median
$42.66
Typical High
$53.70
Hally Health
Setting
Professional
Modifier
None
Typical Low
$22.39
Median
$39.81
Typical High
$93.33
Medica
Setting
Facility
Modifier
None
Typical Low
$26.30
Median
$33.11
Typical High
$64.57
Medica
Setting
Professional
Modifier
None
Typical Low
$13.18
Median
$22.91
Typical High
$51.29
Midlands
Setting
Professional
Modifier
None
Typical Low
$21.88
Median
$27.54
Typical High
$29.51
Midlands
Setting
Facility
Modifier
None
Typical Low
$21.88
Median
$21.88
Typical High
$21.88
United
Setting
Facility
Modifier
None
Typical Low
$22.39
Median
$22.39
Typical High
$56.23
United
Setting
Professional
Modifier
None
Typical Low
$13.18
Median
$15.85
Typical High
$26.30
Wellmark
Setting
Professional
Modifier
None
Typical Low
$17.38
Median
$22.39
Typical High
$22.39

Where Iowa sits

The same service costs 5.0 times more in Alaska than in Georgia. Every bar is a state, most expensive first. Touch or drag across it to read any state, then open that state for its carriers and full range.

Iowa· 12th of 51

$26.30

AK $50.12GA $10.00

Median negotiated rate in each state, from every insurer that publishes one. States where no insurer publishes a rate for this service are not shown.