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Enzyme Activity Test, Blood or Tissue

Florida rates for HCPCS 82657

This is a laboratory test that measures how active a specific enzyme is in a blood, cell, or tissue sample, used when a more common, individually named enzyme test does not apply. It can help diagnose or monitor certain metabolic or inherited conditions where a particular enzyme is missing or not working properly.

Rates data updated October 2026.

How much does Enzyme Activity Test, Blood or Tissue cost?

$18.20

Typical negotiated rate. In Florida, October 2026.

Insurers have agreed to pay about $18.20 for this service. The price depends on where it is billed: about $14.45 from a physician practice, and about $40.74 from a hospital or other facility.

These are rates insurers have negotiated with providers, not the amount a patient is billed. What you owe depends on your plan's deductible and coinsurance. Based on rates published by 8 insurance carriers under federal price transparency rules.

Prices by location type

Billed byTypicalRange
Physician practiceA doctor's office, clinic or independent provider$14.45$12.02 to $22.39
FacilityA hospital or hospital-owned outpatient department$40.74$22.39 to $40.74

How much rates vary

Facilitymedian $41 · 10th to 90th $17 to $95Professionalmedian $14 · 10th to 90th $9 to $40
$10$20$50$100facility $41professional $14

Distribution of negotiated rates across all payers (price axis is log-scale). Need provider-level prices or 24+ months of history? Contact us.

Rates by insurance carrier

Insurance Carrier
Aetna
Setting
Facility
Modifier
None
Typical Low
$14.45
Median
$16.22
Typical High
$47.86
Aetna
Setting
Professional
Modifier
None
Typical Low
$14.45
Median
$16.22
Typical High
$19.95
Aetna
Setting
Professional
Modifier
52 · Reduced service
Typical Low
$7.24
Median
$7.94
Typical High
$9.33
Aetna
Setting
Professional
Modifier
53 · Discontinued
Typical Low
$2.88
Median
$3.24
Typical High
$3.80
Ambetter
Setting
Professional
Modifier
None
Typical Low
$12.02
Median
$13.49
Typical High
$13.49
AvMed
Setting
Facility
Modifier
None
Typical Low
$17.78
Median
$22.39
Typical High
$26.92
AvMed
Setting
Professional
Modifier
None
Typical Low
$17.78
Median
$22.39
Typical High
$25.70
Cigna
Setting
Facility
Modifier
None
Typical Low
$14.45
Median
$22.39
Typical High
$91.20
Cigna
Setting
Professional
Modifier
None
Typical Low
$11.22
Median
$19.95
Typical High
$39.81
Florida Blue
Setting
Facility
Modifier
None
Typical Low
$18.20
Median
$40.74
Typical High
$112.20
Florida Blue
Setting
Professional
Modifier
None
Typical Low
$13.18
Median
$14.13
Typical High
$24.55
Molina
Setting
Professional
Modifier
None
Typical Low
$2.63
Median
$10.72
Typical High
$15.49
United
Setting
Facility
Modifier
None
Typical Low
$22.39
Median
$22.39
Typical High
$22.39
United
Setting
Professional
Modifier
None
Typical Low
$8.51
Median
$12.59
Typical High
$54.95
Wellpoint
Setting
Professional
Modifier
None
Typical Low
$13.18
Median
$13.18
Typical High
$22.39

Where Florida sits

The same service costs 5.0 times more in Alaska than in Georgia. Every bar is a state, most expensive first. Touch or drag across it to read any state, then open that state for its carriers and full range.

Florida· 36th of 51

$18.20

AK $50.12GA $10.00

Median negotiated rate in each state, from every insurer that publishes one. States where no insurer publishes a rate for this service are not shown.