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Enzyme Activity Test, Blood or Tissue

Florida rates for HCPCS 82657

This is a laboratory test that measures how active a specific enzyme is in a blood, cell, or tissue sample, used when a more common, individually named enzyme test does not apply. It can help diagnose or monitor certain metabolic or inherited conditions where a particular enzyme is missing or not working properly.

Rates data updated July 2026.

How much does Enzyme Activity Test, Blood or Tissue cost?

$19.50

Typical negotiated rate. In Florida, July 2026.

Insurers have agreed to pay about $19.50 for this service. The price depends on where it is billed: about $15.85 from a physician practice, and about $67.61 from a hospital or other facility. The two figures are alternatives, not parts of one bill.

These are rates insurers have negotiated with providers, not the amount a patient is billed. What you owe depends on your plan's deductible and coinsurance. Based on rates published by 8 insurance carriers under federal price transparency rules.

Where it's billed changes the price

Billed byTypicalRange
Physician practiceA doctor's office, clinic or independent provider$15.85$14.45 to $16.98
FacilityA hospital or hospital-owned outpatient department$67.61$33.11 to $145

How much rates vary

Facilitymedian $68 · 10th to 90th $18 to $251Professionalmedian $16 · 10th to 90th $14 to $25
$5.0$20.0$100.0$500.0facility $68professional $16

Distribution of negotiated rates across all payers (price axis is log-scale). Each curve is scaled to its own total: facility and professional rates are different services, shown together to compare where they cluster. Need provider-level prices or 24+ months of history? Contact us.

Rates by insurance carrier

Insurance Carrier
Aetna
Setting
Facility
Modifier
Global
Typical Low
$19.05
Median
$83.18
Typical High
$288.40
Aetna
Setting
Professional
Modifier
Global
Typical Low
$14.45
Median
$16.22
Typical High
$21.38
Ambetter
Setting
Professional
Modifier
Global
Typical Low
$12.02
Median
$13.49
Typical High
$13.49
AvMed
Setting
Facility
Modifier
Global
Typical Low
$19.50
Median
$22.39
Typical High
$26.30
AvMed
Setting
Professional
Modifier
Global
Typical Low
$17.78
Median
$22.39
Typical High
$24.55
Cigna
Setting
Facility
Modifier
Global
Typical Low
$14.45
Median
$22.39
Typical High
$64.57
Cigna
Setting
Professional
Modifier
Global
Typical Low
$10.96
Median
$19.95
Typical High
$39.81
Florida Blue
Setting
Facility
Modifier
Global
Typical Low
$20.89
Median
$40.74
Typical High
$131.83
Florida Blue
Setting
Professional
Modifier
Global
Typical Low
$13.18
Median
$13.18
Typical High
$24.55
Molina
Setting
Professional
Modifier
Global
Typical Low
$2.63
Median
$10.72
Typical High
$13.18
United
Setting
Facility
Modifier
Global
Typical Low
$9.33
Median
$19.95
Typical High
$22.39
United
Setting
Professional
Modifier
Global
Typical Low
$8.32
Median
$10.72
Typical High
$25.12
Wellpoint
Setting
Professional
Modifier
Global
Typical Low
$13.18
Median
$13.18
Typical High
$22.39

Where Florida sits

The same service costs 3.5 times more in Iowa than in Maryland. Every bar is a state, most expensive first. Pick one to see its carriers and full range.

Florida $19.50 · 44th of 51
IA $58.88MD $16.60

Median negotiated rate in each state, from every insurer that publishes one. States where no insurer publishes a rate for this service are not shown.