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Enzyme Activity Test, Blood or Tissue

Colorado rates for HCPCS 82657

This is a laboratory test that measures how active a specific enzyme is in a blood, cell, or tissue sample, used when a more common, individually named enzyme test does not apply. It can help diagnose or monitor certain metabolic or inherited conditions where a particular enzyme is missing or not working properly.

Rates data updated July 2026.

How much does Enzyme Activity Test, Blood or Tissue cost?

$20.89

Typical negotiated rate. In Colorado, July 2026.

Insurers have agreed to pay about $20.89 for this service. The price depends on where it is billed: about $16.98 from a physician practice, and about $64.57 from a hospital or other facility. The two figures are alternatives, not parts of one bill.

These are rates insurers have negotiated with providers, not the amount a patient is billed. What you owe depends on your plan's deductible and coinsurance. Based on rates published by 7 insurance carriers under federal price transparency rules.

Where it's billed changes the price

Billed byTypicalRange
Physician practiceA doctor's office, clinic or independent provider$16.98$16.22 to $19.05
FacilityA hospital or hospital-owned outpatient department$64.57$33.11 to $102

How much rates vary

Facilitymedian $65 · 10th to 90th $17 to $174Professionalmedian $17 · 10th to 90th $9 to $21
$10.0$20.0$50.0$100.0$200.0$500.0$1.0Kfacility $65professional $17

Distribution of negotiated rates across all payers (price axis is log-scale). Each curve is scaled to its own total: facility and professional rates are different services, shown together to compare where they cluster. Need provider-level prices or 24+ months of history? Contact us.

Rates by insurance carrier

Insurance Carrier
Aetna
Setting
Facility
Modifier
Global
Typical Low
$16.98
Median
$77.62
Typical High
$489.78
Aetna
Setting
Professional
Modifier
Global
Typical Low
$16.22
Median
$16.98
Typical High
$20.89
Anthem BCBS
Setting
Facility
Modifier
Global
Typical Low
$27.54
Median
$66.07
Typical High
$112.20
Anthem BCBS
Setting
Professional
Modifier
Global
Typical Low
$8.91
Median
$9.33
Typical High
$16.98
Cigna
Setting
Facility
Modifier
Global
Typical Low
$11.75
Median
$15.49
Typical High
$58.88
Cigna
Setting
Professional
Modifier
Global
Typical Low
$11.22
Median
$12.30
Typical High
$26.30
Denver HMP
Setting
Facility
Modifier
Global
Typical Low
$16.98
Median
$23.99
Typical High
$45.71
Kaiser Permanente
Setting
Professional
Modifier
Global
Typical Low
$31.62
Median
$114.82
Typical High
$114.82
Select Health
Setting
Facility
Modifier
Global
Typical Low
$23.44
Median
$40.74
Typical High
$46.77
Select Health
Setting
Professional
Modifier
Global
Typical Low
$15.49
Median
$15.49
Typical High
$22.39
United
Setting
Facility
Modifier
Global
Typical Low
$13.49
Median
$22.39
Typical High
$33.11
United
Setting
Professional
Modifier
Global
Typical Low
$9.33
Median
$10.72
Typical High
$20.89

Where Colorado sits

The same service costs 3.5 times more in Iowa than in Maryland. Every bar is a state, most expensive first. Pick one to see its carriers and full range.

Colorado $20.89 · 41st of 51
IA $58.88MD $16.60

Median negotiated rate in each state, from every insurer that publishes one. States where no insurer publishes a rate for this service are not shown.