go back

Enzyme Activity Test, Blood or Tissue

Alabama rates for HCPCS 82657

This is a laboratory test that measures how active a specific enzyme is in a blood, cell, or tissue sample, used when a more common, individually named enzyme test does not apply. It can help diagnose or monitor certain metabolic or inherited conditions where a particular enzyme is missing or not working properly.

Rates data updated October 2026.

How much does Enzyme Activity Test, Blood or Tissue cost?

$17.78

Typical negotiated rate. In Alabama, October 2026.

Insurers have agreed to pay about $17.78 for this service. The price depends on where it is billed: about $14.45 from a physician practice, and about $17.78 from a hospital or other facility.

These are rates insurers have negotiated with providers, not the amount a patient is billed. What you owe depends on your plan's deductible and coinsurance. Based on rates published by 4 insurance carriers under federal price transparency rules.

Prices by location type

Billed byTypicalRange
Physician practiceA doctor's office, clinic or independent provider$14.45$10.72 to $25.70
FacilityA hospital or hospital-owned outpatient department$17.78$17.78 to $17.78

How much rates vary

Facilitymedian $18 · 10th to 90th $18 to $19Professionalmedian $14 · 10th to 90th $9 to $26
$10$20$50$100facility $18professional $14

Distribution of negotiated rates across all payers (price axis is log-scale). Need provider-level prices or 24+ months of history? Contact us.

Rates by insurance carrier

Insurance Carrier
Aetna
Setting
Facility
Modifier
None
Typical Low
$25.70
Median
$25.70
Typical High
$33.88
Aetna
Setting
Professional
Modifier
None
Typical Low
$10.96
Median
$25.70
Typical High
$25.70
BCBS Alabama
Setting
Facility
Modifier
None
Typical Low
$17.78
Median
$17.78
Typical High
$17.78
BCBS Alabama
Setting
Professional
Modifier
21 + 22 · Increased work + 24 · Unrelated visit after surgery + 31
Typical Low
$12.59
Median
$15.14
Typical High
$18.62
Cigna
Setting
Facility
Modifier
None
Typical Low
$18.20
Median
$18.62
Typical High
$70.79
Cigna
Setting
Professional
Modifier
None
Typical Low
$9.33
Median
$11.22
Typical High
$102.33
United
Setting
Facility
Modifier
None
Typical Low
$7.94
Median
$19.95
Typical High
$22.39
United
Setting
Professional
Modifier
None
Typical Low
$9.33
Median
$10.96
Typical High
$14.79
2 more rates with less common billing modifiers

A modifier changes what was billed, for example a reduced or repeated service. Each of these modifiers carries under 10% of the published rates for this code. Modifier combinations, and modifiers with fewer than 30 rates for a carrier, are not listed.

Insurance Carrier
Aetna
Setting
Professional
Modifier
52 · Reduced service
Typical Low
$9.12
Median
$12.88
Typical High
$12.88
Aetna
Setting
Professional
Modifier
53 · Discontinued
Typical Low
$3.63
Median
$5.13
Typical High
$5.13

Where Alabama sits

The same service costs 5.0 times more in Alaska than in Georgia. Every bar is a state, most expensive first. Touch or drag across it to read any state, then open that state for its carriers and full range.

Alabama· 41st of 51

$17.78

AK $50.12GA $10.00

Median negotiated rate in each state, from every insurer that publishes one. States where no insurer publishes a rate for this service are not shown.