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Cryoglobulin Blood Test

South Dakota rates for HCPCS 82595

A blood test that checks for abnormal proteins which clump together when blood cools below body temperature and dissolve again once it is warmed. Finding them can point to certain autoimmune conditions, some blood cancers, or long-standing infections such as hepatitis C. The sample has to be kept warm on its way to the laboratory, or the proteins drop out and the result can read as normal when it is not.

Rates data updated July 2026.

Facilitymedian $55 · 10th–90th $8$780%20%10th90th$55Professionalmedian $17 · 10th–90th $4$630%10%10th90th$17$5.0$10.0$20.0$50.0$100.0

Distribution of negotiated rates across all payers (price axis is log-scale). Facility and professional rates are different services and are charted separately. Need provider-level prices? Contact us.

Insurance Carrier
Aetna
Setting
Facility
Modifier
Global
Typical Low
$30.20
Median
$54.95
Typical High
$77.62
Aetna
Setting
Professional
Modifier
Global
Typical Low
$4.37
Median
$34.67
Typical High
$63.10
Avera
Setting
Facility
Modifier
Global
Typical Low
$5.89
Median
$6.61
Typical High
$9.77
Cigna
Setting
Facility
Modifier
Global
Typical Low
$12.30
Median
$12.30
Typical High
$12.30
Cigna
Setting
Professional
Modifier
Global
Typical Low
$7.41
Median
$12.30
Typical High
$15.49
Medica
Setting
Facility
Modifier
Global
Typical Low
$6.17
Median
$10.47
Typical High
$52.48
Medica
Setting
Professional
Modifier
Global
Typical Low
$3.24
Median
$4.47
Typical High
$9.12
Sanford Health Plan
Setting
Professional
Modifier
Global
Typical Low
$9.77
Median
$15.49
Typical High
$17.78
United
Setting
Facility
Modifier
Global
Typical Low
$7.76
Median
$7.76
Typical High
$7.76
United
Setting
Professional
Modifier
Global
Typical Low
$2.69
Median
$4.47
Typical High
$10.96
Wellmark
Setting
Professional
Modifier
Global
Typical Low
$6.46
Median
$6.46
Typical High
$6.46