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Alpha-Fetoprotein (AFP) Blood Test

South Dakota rates for HCPCS 82105

This blood test measures alpha-fetoprotein, a protein that is normally high in a developing fetus and typically low in adults. In adults it can be used as a tumor marker, particularly for liver cancer, while during pregnancy it can be part of screening for certain birth conditions.

Rates data updated July 2026.

How much does Alpha-Fetoprotein (AFP) Blood Test cost?

$45.71

Typical negotiated rate. In South Dakota, July 2026.

Insurers have agreed to pay about $45.71 for this service. The price depends on where it is billed: about $25.12 from a physician practice, and about $89.13 from a hospital or other facility. The two figures are alternatives, not parts of one bill.

These are rates insurers have negotiated with providers, not the amount a patient is billed. What you owe depends on your plan's deductible and coinsurance. Based on rates published by 7 insurance carriers under federal price transparency rules.

Where it's billed changes the price

Billed byTypicalRange
Physician practiceA doctor's office, clinic or independent provider$25.12$15.14 to $91.20
FacilityA hospital or hospital-owned outpatient department$89.13$74.13 to $145

How much rates vary

Facilitymedian $89 · 10th to 90th $32 to $229Professionalmedian $25 · 10th to 90th $14 to $126
$20$50$100$200$500facility $89professional $25

Distribution of negotiated rates across all payers (price axis is log-scale). Each curve is scaled to its own total: facility and professional rates are different services, shown together to compare where they cluster. Need provider-level prices or 24+ months of history? Contact us.

Rates by insurance carrier

Insurance Carrier
Aetna
Setting
Facility
Modifier
Global
Typical Low
$74.13
Median
$100.00
Typical High
$229.09
Aetna
Setting
Professional
Modifier
Global
Typical Low
$14.45
Median
$19.50
Typical High
$128.82
Avera
Setting
Facility
Modifier
Global
Typical Low
$15.49
Median
$16.98
Typical High
$25.12
Avera
Setting
Professional
Modifier
Global
Typical Low
$14.45
Median
$16.98
Typical High
$17.78
Cigna
Setting
Facility
Modifier
Global
Typical Low
$32.36
Median
$32.36
Typical High
$32.36
Cigna
Setting
Professional
Modifier
Global
Typical Low
$19.50
Median
$32.36
Typical High
$40.74
Medica
Setting
Facility
Modifier
Global
Typical Low
$16.22
Median
$26.92
Typical High
$173.78
Medica
Setting
Professional
Modifier
Global
Typical Low
$10.00
Median
$11.75
Typical High
$23.44
Sanford Health Plan
Setting
Professional
Modifier
Global
Typical Low
$25.12
Median
$40.74
Typical High
$45.71
United
Setting
Facility
Modifier
Global
Typical Low
$19.95
Median
$19.95
Typical High
$19.95
United
Setting
Professional
Modifier
Global
Typical Low
$7.08
Median
$15.14
Typical High
$23.44
Wellmark
Setting
Professional
Modifier
Global
Typical Low
$16.60
Median
$16.60
Typical High
$16.60

Where South Dakota sits

The same service costs 8.7 times more in West Virginia than in Wyoming. Every bar is a state, most expensive first. Touch or drag across it to read any state, then open that state for its carriers and full range.

South Dakota· 5th of 51

$45.71

WV $135WY $15.49

Median negotiated rate in each state, from every insurer that publishes one. States where no insurer publishes a rate for this service are not shown.