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Alpha-Fetoprotein (AFP) Blood Test

North Carolina rates for HCPCS 82105

This blood test measures alpha-fetoprotein, a protein that is normally high in a developing fetus and typically low in adults. In adults it can be used as a tumor marker, particularly for liver cancer, while during pregnancy it can be part of screening for certain birth conditions.

Rates data updated October 2026.

How much does Alpha-Fetoprotein (AFP) Blood Test cost?

$13.49

Typical negotiated rate. In North Carolina, October 2026.

Insurers have agreed to pay about $13.49 for this service. The price depends on where it is billed: about $13.49 from a physician practice, and about $16.60 from a hospital or other facility.

These are rates insurers have negotiated with providers, not the amount a patient is billed. What you owe depends on your plan's deductible and coinsurance. Based on rates published by 7 insurance carriers under federal price transparency rules.

Prices by location type

Billed byTypicalRange
Physician practiceA doctor's office, clinic or independent provider$13.49$11.22 to $16.60
FacilityA hospital or hospital-owned outpatient department$16.60$13.49 to $33.11

How much rates vary

Facilitymedian $17 · 10th to 90th $13 to $55Professionalmedian $13 · 10th to 90th $8 to $25
$5$10$20$50facility $17professional $13

Distribution of negotiated rates across all payers (price axis is log-scale). Need provider-level prices or 24+ months of history? Contact us.

Rates by insurance carrier

Insurance Carrier
Aetna
Setting
Facility
Modifier
None
Typical Low
$13.49
Median
$14.45
Typical High
$35.48
Aetna
Setting
Professional
Modifier
None
Typical Low
$13.49
Median
$13.49
Typical High
$22.39
Aetna
Setting
Professional
Modifier
52 · Reduced service
Typical Low
$6.76
Median
$6.76
Typical High
$7.24
Aetna
Setting
Professional
Modifier
53 · Discontinued
Typical Low
$2.69
Median
$2.69
Typical High
$2.88
Ambetter
Setting
Professional
Modifier
None
Typical Low
$4.17
Median
$4.17
Typical High
$11.75
BCBS North Carolina
Setting
Facility
Modifier
None
Typical Low
$28.18
Median
$37.15
Typical High
$53.70
BCBS North Carolina
Setting
Professional
Modifier
None
Typical Low
$7.59
Median
$7.59
Typical High
$10.96
Cigna
Setting
Facility
Modifier
None
Typical Low
$11.75
Median
$37.15
Typical High
$75.86
Cigna
Setting
Professional
Modifier
None
Typical Low
$8.71
Median
$11.22
Typical High
$27.54
Medcost
Setting
Professional
Modifier
None
Typical Low
$13.80
Median
$30.90
Typical High
$33.11
Medcost
Setting
Facility
Modifier
None
Typical Low
$12.02
Median
$13.49
Typical High
$35.48
Medcost
Setting
Professional
Modifier
None
Typical Low
$13.49
Median
$23.99
Typical High
$30.90
Oscar Health
Setting
Facility
Modifier
None
Typical Low
$13.18
Median
$13.18
Typical High
$13.18
United
Setting
Professional
Modifier
None
Typical Low
$7.08
Median
$11.75
Typical High
$22.91

Where North Carolina sits

The same service costs 7.9 times more in Vermont than in Maryland. Every bar is a state, most expensive first. Touch or drag across it to read any state, then open that state for its carriers and full range.

North Carolina· 48th of 51

$13.49

VT $100MD $12.59

Median negotiated rate in each state, from every insurer that publishes one. States where no insurer publishes a rate for this service are not shown.