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Alpha-Fetoprotein (AFP) Blood Test

Illinois rates for HCPCS 82105

This blood test measures alpha-fetoprotein, a protein that is normally high in a developing fetus and typically low in adults. In adults it can be used as a tumor marker, particularly for liver cancer, while during pregnancy it can be part of screening for certain birth conditions.

Rates data updated October 2026.

How much does Alpha-Fetoprotein (AFP) Blood Test cost?

$12.88

Typical negotiated rate. In Illinois, October 2026.

Insurers have agreed to pay about $12.88 for this service. The price depends on where it is billed: about $12.88 from a physician practice, and about $37.15 from a hospital or other facility.

These are rates insurers have negotiated with providers, not the amount a patient is billed. What you owe depends on your plan's deductible and coinsurance. Based on rates published by 7 insurance carriers under federal price transparency rules.

Prices by location type

Billed byTypicalRange
Physician practiceA doctor's office, clinic or independent provider$12.88$10.00 to $13.80
FacilityA hospital or hospital-owned outpatient department$37.15$22.39 to $61.66

How much rates vary

Facilitymedian $37 · 10th to 90th $17 to $107Professionalmedian $13 · 10th to 90th $3 to $23
$5$10$20$50$100$200facility $37professional $13

Distribution of negotiated rates across all payers (price axis is log-scale). Need provider-level prices or 24+ months of history? Contact us.

Rates by insurance carrier

Insurance Carrier
Aetna
Setting
Facility
Modifier
None
Typical Low
$13.80
Median
$23.44
Typical High
$50.12
Aetna
Setting
Professional
Modifier
None
Typical Low
$13.49
Median
$14.45
Typical High
$23.44
Ambetter
Setting
Professional
Modifier
None
Typical Low
$8.32
Median
$8.32
Typical High
$22.39
BCBS Illinois
Setting
Facility
Modifier
None
Typical Low
$22.39
Median
$50.12
Typical High
$173.78
BCBS Illinois
Setting
Professional
Modifier
None
Typical Low
$3.47
Median
$12.88
Typical High
$12.88
Cigna
Setting
Facility
Modifier
None
Typical Low
$18.62
Median
$38.90
Typical High
$69.18
Cigna
Setting
Professional
Modifier
None
Typical Low
$8.71
Median
$19.50
Typical High
$30.20
Hally Health
Setting
Professional
Modifier
None
Typical Low
$17.78
Median
$29.51
Typical High
$162.18
Hally Health
Setting
Facility
Modifier
None
Typical Low
$100.00
Median
$100.00
Typical High
$100.00
Hally Health
Setting
Professional
Modifier
None
Typical Low
$21.88
Median
$21.88
Typical High
$21.88
Molina
Setting
Professional
Modifier
None
Typical Low
$9.12
Median
$9.12
Typical High
$20.89
United
Setting
Facility
Modifier
None
Typical Low
$16.60
Median
$19.95
Typical High
$42.66
United
Setting
Professional
Modifier
None
Typical Low
$7.08
Median
$12.59
Typical High
$18.20
4 more rates with less common billing modifiers

A modifier changes what was billed, for example a reduced or repeated service. Each of these modifiers carries under 10% of the published rates for this code. Modifier combinations, and modifiers with fewer than 30 rates for a carrier, are not listed.

Insurance Carrier
Aetna
Setting
Facility
Modifier
52 · Reduced service
Typical Low
$6.92
Median
$12.02
Typical High
$25.12
Aetna
Setting
Facility
Modifier
53 · Discontinued
Typical Low
$2.75
Median
$4.90
Typical High
$10.23
Aetna
Setting
Professional
Modifier
52 · Reduced service
Typical Low
$6.92
Median
$6.92
Typical High
$8.32
Aetna
Setting
Professional
Modifier
53 · Discontinued
Typical Low
$2.75
Median
$2.75
Typical High
$3.39

Where Illinois sits

The same service costs 7.9 times more in Vermont than in Maryland. Every bar is a state, most expensive first. Touch or drag across it to read any state, then open that state for its carriers and full range.

Illinois· 50th of 51

$12.88

VT $100MD $12.59

Median negotiated rate in each state, from every insurer that publishes one. States where no insurer publishes a rate for this service are not shown.