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Thyroid Nodule Gene Activity Test

Indiana rates for HCPCS 81546

Analyzes the activity of a large number of genes in cells drawn out of a thyroid nodule with a fine needle. It is used when the usual microscope examination of those cells could not say whether the nodule is harmless, and the result is reported as benign or suspicious to help decide whether surgery is needed.

Rates data updated July 2026.

How much does Thyroid Nodule Gene Activity Test cost?

$2,951

Typical negotiated rate. In Indiana, July 2026.

Insurers have agreed to pay about $2,951 for this service. The price depends on where it is billed: about $2,951 from a physician practice, and about $3,631 from a hospital or other facility. The two figures are alternatives, not parts of one bill.

These are rates insurers have negotiated with providers, not the amount a patient is billed. What you owe depends on your plan's deductible and coinsurance. Based on rates published by 4 insurance carriers under federal price transparency rules.

Where it's billed changes the price

Billed byTypicalRange
Physician practiceA doctor's office, clinic or independent provider$2,951$2,138 to $2,951
FacilityA hospital or hospital-owned outpatient department$3,631$3,631 to $7,244

How much rates vary

Facilitymedian $3,631 · 10th to 90th $3,236 to $10,715Professionalmedian $2,951 · 10th to 90th $1,445 to $3,631
$10.0$100.0$1.0K$10.0Kfacility $3,631professional $2,951

Distribution of negotiated rates across all payers (price axis is log-scale). Each curve is scaled to its own total: facility and professional rates are different services, shown together to compare where they cluster. Need provider-level prices or 24+ months of history? Contact us.

Rates by insurance carrier

Insurance Carrier
Aetna
Setting
Facility
Modifier
Global
Typical Low
$2,951.21
Median
$5,623.41
Typical High
$10,715.19
Aetna
Setting
Professional
Modifier
Global
Typical Low
$2,818.38
Median
$2,951.21
Typical High
$3,388.44
Anthem BCBS
Setting
Facility
Modifier
Global
Typical Low
$3,630.78
Median
$3,630.78
Typical High
$10,715.19
Anthem BCBS
Setting
Professional
Modifier
Global
Typical Low
$1,445.44
Median
$1,445.44
Typical High
$3,019.95
Cigna
Setting
Facility
Modifier
Global
Typical Low
$2,344.23
Median
$3,235.94
Typical High
$10,000.00
Cigna
Setting
Professional
Modifier
Global
Typical Low
$1,659.59
Median
$3,235.94
Typical High
$5,248.07
United
Setting
Facility
Modifier
Global
Typical Low
$3,630.78
Median
$3,630.78
Typical High
$4,168.69
United
Setting
Professional
Modifier
Global
Typical Low
$1,513.56
Median
$2,137.96
Typical High
$4,365.16

Where Indiana sits

The same service costs 3.4 times more in Alaska than in Delaware. Every bar is a state, most expensive first. Pick one to see its carriers and full range.

Indiana $2,951 · 40th of 51
AK $8,128DE $2,399

Median negotiated rate in each state, from every insurer that publishes one. States where no insurer publishes a rate for this service are not shown.