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Thyroid Nodule Gene Activity Test

Minnesota rates for HCPCS 81545

A laboratory test run on thyroid cells collected through a fine needle. It measures how active a large set of genes is in those cells and returns one overall answer - benign, or suspicious - to help decide whether a nodule with an unclear needle result needs to come out.

Rates data updated July 2026.

How much does Thyroid Nodule Gene Activity Test cost?

$5,129

Typical negotiated rate. In Minnesota, July 2026.

Insurers have agreed to pay about $5,129 for this service. The price depends on where it is billed: about $4,266 from a physician practice, and about $12,023 from a hospital or other facility. The two figures are alternatives, not parts of one bill.

These are rates insurers have negotiated with providers, not the amount a patient is billed. What you owe depends on your plan's deductible and coinsurance. Based on rates published by 3 insurance carriers under federal price transparency rules.

Where it's billed changes the price

Billed byTypicalRange
Physician practiceA doctor's office, clinic or independent provider$4,266$4,266 to $6,026
FacilityA hospital or hospital-owned outpatient department$12,023$10,000 to $27,542

How much rates vary

Facilitymedian $12,023 · 10th to 90th $7,762 to $27,542Professionalmedian $4,266 · 10th to 90th $4,266 to $7,079
$5.0K$10.0K$20.0Kfacility $12,023professional $4,266

Distribution of negotiated rates across all payers (price axis is log-scale). Each curve is scaled to its own total: facility and professional rates are different services, shown together to compare where they cluster. Need provider-level prices or 24+ months of history? Contact us.

Rates by insurance carrier

Insurance Carrier
Cigna
Setting
Facility
Modifier
Global
Typical Low
$7,413.10
Median
$12,589.25
Typical High
$34,673.69
Cigna
Setting
Professional
Modifier
Global
Typical Low
$4,265.80
Median
$5,370.32
Typical High
$7,585.78
Health Partners
Setting
Facility
Modifier
Global
Typical Low
$8,128.31
Median
$11,748.98
Typical High
$27,542.29
Health Partners
Setting
Professional
Modifier
Global
Typical Low
$4,265.80
Median
$4,265.80
Typical High
$7,079.46
Medica
Setting
Facility
Modifier
Global
Typical Low
$8,511.38
Median
$8,511.38
Typical High
$8,511.38
Medica
Setting
Professional
Modifier
Global
Typical Low
$12,589.25
Median
$12,589.25
Typical High
$12,589.25

Where Minnesota sits

The same service costs 2187.8 times more in Illinois than in Florida. Every bar is a state, most expensive first. Pick one to see its carriers and full range.

Minnesota $5,129 · 18th of 33
IL $23,988FL $10.96

Median negotiated rate in each state, from every insurer that publishes one. States where no insurer publishes a rate for this service are not shown.