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Thyroid Nodule Gene Activity Test

Massachusetts rates for HCPCS 81545

A laboratory test run on thyroid cells collected through a fine needle. It measures how active a large set of genes is in those cells and returns one overall answer - benign, or suspicious - to help decide whether a nodule with an unclear needle result needs to come out.

Rates data updated July 2026.

How much does Thyroid Nodule Gene Activity Test cost?

$16,218

Typical negotiated rate. In Massachusetts, July 2026.

Insurers have agreed to pay about $16,218 for this service. Most negotiated rates run $8,913 to $16,218.

Few insurers publish rates for this combination, so treat this figure as a rough guide.

These are rates insurers have negotiated with providers, not the amount a patient is billed. What you owe depends on your plan's deductible and coinsurance. Based on rates published by 3 insurance carriers under federal price transparency rules.

How much rates vary

Facilitymedian $8,913 · 10th to 90th $8,913 to $8,913Professionalmedian $16,218 · 10th to 90th $4,467 to $16,218
$5K$10Kfacility $8,913professional $16,218

Distribution of negotiated rates across all payers (price axis is log-scale). Each curve is scaled to its own total: facility and professional rates are different services, shown together to compare where they cluster. Small sample; interpret with caution. Need provider-level prices or 24+ months of history? Contact us.

Rates by insurance carrier

Insurance Carrier
AllWays Health Partners
Setting
Facility
Modifier
Global
Typical Low
$8,912.51
Median
$8,912.51
Typical High
$8,912.51
AllWays Health Partners
Setting
Professional
Modifier
Global
Typical Low
$16,218.10
Median
$16,218.10
Typical High
$16,218.10
Cigna
Setting
Professional
Modifier
Global
Typical Low
$4,265.80
Median
$4,466.84
Typical High
$5,370.32
Mass General Brigham
Setting
Facility
Modifier
Global
Typical Low
$8,912.51
Median
$8,912.51
Typical High
$8,912.51
Mass General Brigham
Setting
Professional
Modifier
Global
Typical Low
$16,218.10
Median
$16,218.10
Typical High
$16,218.10

Where Massachusetts sits

The same service costs 2187.8 times more in Illinois than in Florida. Every bar is a state, most expensive first. Touch or drag across it to read any state, then open that state for its carriers and full range.

Massachusetts· 2nd of 33

$16,218

IL $23,988FL $10.96

Median negotiated rate in each state, from every insurer that publishes one. States where no insurer publishes a rate for this service are not shown.