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Tumor Cell Drug Response Test, First Drug

South Dakota rates for HCPCS 81535

A laboratory test that keeps living cancer cells taken from a gynecologic tumor alive in culture and exposes them to a cancer drug to see how strongly the cells react. The reaction is reported as a score that helps the oncologist judge which drug is more likely to work against that particular tumor. This covers the first drug or drug combination tested.

Rates data updated October 2026.

How much does Tumor Cell Drug Response Test, First Drug cost?

$661

Typical negotiated rate. In South Dakota, October 2026.

Insurers have agreed to pay about $661 for this service. The price depends on where it is billed: about $575 from a physician practice, and about $661 from a hospital or other facility.

These are rates insurers have negotiated with providers, not the amount a patient is billed. What you owe depends on your plan's deductible and coinsurance. Based on rates published by 6 insurance carriers under federal price transparency rules.

Prices by location type

Billed byTypicalRange
Physician practiceA doctor's office, clinic or independent provider$575$389 to $1,122
FacilityA hospital or hospital-owned outpatient department$661$661 to $1,122

How much rates vary

Facilitymedian $661 · 10th to 90th $550 to $1,122Professionalmedian $575 · 10th to 90th $295 to $1,380
$500$1K$2Kfacility $661professional $575

Distribution of negotiated rates across all payers (price axis is log-scale). Small sample; interpret with caution. Need provider-level prices or 24+ months of history? Contact us.

Rates by insurance carrier

Insurance Carrier
Aetna
Setting
Facility
Modifier
None
Typical Low
$407.38
Median
$407.38
Typical High
$660.69
Aetna
Setting
Professional
Modifier
None
Typical Low
$389.05
Median
$389.05
Typical High
$549.54
Cigna
Setting
Facility
Modifier
None
Typical Low
$1,122.02
Median
$1,122.02
Typical High
$1,122.02
Cigna
Setting
Professional
Modifier
None
Typical Low
$660.69
Median
$1,122.02
Typical High
$1,380.38
Medica
Setting
Facility
Modifier
None
Typical Low
$549.54
Median
$660.69
Typical High
$1,621.81
Medica
Setting
Professional
Modifier
None
Typical Low
$295.12
Median
$524.81
Typical High
$691.83
Sanford Health Plan
Setting
Professional
Modifier
None
Typical Low
$870.96
Median
$1,348.96
Typical High
$1,584.89
United
Setting
Professional
Modifier
None
Typical Low
$245.47
Median
$346.74
Typical High
$575.44
Wellmark
Setting
Professional
Modifier
None
Typical Low
$575.44
Median
$575.44
Typical High
$575.44

Where South Dakota sits

The same service costs 4.5 times more in Alaska than in Oklahoma. Every bar is a state, most expensive first. Touch or drag across it to read any state, then open that state for its carriers and full range.

South Dakota· 12th of 51

$661

AK $1,318OK $295

Median negotiated rate in each state, from every insurer that publishes one. States where no insurer publishes a rate for this service are not shown.