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Breast Cancer Recurrence Risk Gene Score

Missouri rates for HCPCS 81522

Measures the activity of a group of genes in a sample of breast cancer tissue and combines the readings into a score estimating how likely the cancer is to come back. The score is used alongside the usual features of the tumor to help decide whether chemotherapy would add worthwhile benefit on top of hormone treatment.

Rates data updated October 2026.

How much does Breast Cancer Recurrence Risk Gene Score cost?

$3,715

Typical negotiated rate. In Missouri, October 2026.

Insurers have agreed to pay about $3,715 for this service. The price depends on where it is billed: about $3,548 from a physician practice, and about $6,761 from a hospital or other facility.

These are rates insurers have negotiated with providers, not the amount a patient is billed. What you owe depends on your plan's deductible and coinsurance. Based on rates published by 6 insurance carriers under federal price transparency rules.

Prices by location type

Billed byTypicalRange
Physician practiceA doctor's office, clinic or independent provider$3,548$1,905 to $6,166
FacilityA hospital or hospital-owned outpatient department$6,761$4,677 to $10,471

How much rates vary

Facilitymedian $6,761 · 10th to 90th $3,715 to $18,197Professionalmedian $3,548 · 10th to 90th $1,549 to $10,471
$2K$5K$10K$20Kfacility $6,761professional $3,548

Distribution of negotiated rates across all payers (price axis is log-scale). Need provider-level prices or 24+ months of history? Contact us.

Rates by insurance carrier

Insurance Carrier
Aetna
Setting
Facility
Modifier
None
Typical Low
$3,311.31
Median
$5,011.87
Typical High
$7,079.46
Aetna
Setting
Professional
Modifier
None
Typical Low
$3,311.31
Median
$3,311.31
Typical High
$4,466.84
Anthem BCBS
Setting
Facility
Modifier
None
Typical Low
$3,890.45
Median
$3,890.45
Typical High
$17,782.79
Anthem BCBS
Setting
Professional
Modifier
None
Typical Low
$1,548.82
Median
$3,715.35
Typical High
$7,413.10
BCBS Kansas City
Setting
Facility
Modifier
None
Typical Low
$5,370.32
Median
$6,025.60
Typical High
$10,471.29
BCBS Kansas City
Setting
Professional
Modifier
None
Typical Low
$2,691.53
Median
$3,890.45
Typical High
$7,413.10
Cigna
Setting
Facility
Modifier
None
Typical Low
$5,370.32
Median
$8,709.64
Typical High
$31,622.78
Cigna
Setting
Professional
Modifier
None
Typical Low
$1,778.28
Median
$4,365.16
Typical High
$4,570.88
Medica
Setting
Facility
Modifier
None
Typical Low
$3,467.37
Median
$6,760.83
Typical High
$18,197.01
Medica
Setting
Professional
Modifier
None
Typical Low
$1,949.84
Median
$3,981.07
Typical High
$19,498.45
United
Setting
Facility
Modifier
None
Typical Low
$3,467.37
Median
$3,467.37
Typical High
$3,467.37
United
Setting
Professional
Modifier
None
Typical Low
$1,621.81
Median
$2,344.23
Typical High
$5,248.07

Where Missouri sits

The same service costs 11.0 times more in Texas than in Alabama. Every bar is a state, most expensive first. Touch or drag across it to read any state, then open that state for its carriers and full range.

Missouri· 26th of 51

$3,715

TX $17,783AL $1,622

Median negotiated rate in each state, from every insurer that publishes one. States where no insurer publishes a rate for this service are not shown.