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Breast Cancer Recurrence Risk Gene Score

Indiana rates for HCPCS 81522

Measures the activity of a group of genes in a sample of breast cancer tissue and combines the readings into a score estimating how likely the cancer is to come back. The score is used alongside the usual features of the tumor to help decide whether chemotherapy would add worthwhile benefit on top of hormone treatment.

Rates data updated July 2026.

How much does Breast Cancer Recurrence Risk Gene Score cost?

$3,162

Typical negotiated rate. In Indiana, July 2026.

Insurers have agreed to pay about $3,162 for this service. The price depends on where it is billed: about $3,162 from a physician practice, and about $3,890 from a hospital or other facility. The two figures are alternatives, not parts of one bill.

These are rates insurers have negotiated with providers, not the amount a patient is billed. What you owe depends on your plan's deductible and coinsurance. Based on rates published by 4 insurance carriers under federal price transparency rules.

Where it's billed changes the price

Billed byTypicalRange
Physician practiceA doctor's office, clinic or independent provider$3,162$2,188 to $3,162
FacilityA hospital or hospital-owned outpatient department$3,890$3,890 to $7,762

How much rates vary

Facilitymedian $3,890 · 10th to 90th $3,890 to $11,749Professionalmedian $3,162 · 10th to 90th $1,549 to $3,467
$2K$5K$10K$20Kfacility $3,890professional $3,162

Distribution of negotiated rates across all payers (price axis is log-scale). Each curve is scaled to its own total: facility and professional rates are different services, shown together to compare where they cluster. Need provider-level prices or 24+ months of history? Contact us.

Rates by insurance carrier

Insurance Carrier
Aetna
Setting
Facility
Modifier
Global
Typical Low
$3,162.28
Median
$4,265.80
Typical High
$11,748.98
Aetna
Setting
Professional
Modifier
Global
Typical Low
$3,090.30
Median
$3,162.28
Typical High
$3,467.37
Anthem BCBS
Setting
Facility
Modifier
Global
Typical Low
$3,890.45
Median
$3,890.45
Typical High
$11,748.98
Anthem BCBS
Setting
Professional
Modifier
Global
Typical Low
$1,548.82
Median
$1,548.82
Typical High
$3,090.30
Cigna
Setting
Facility
Modifier
Global
Typical Low
$2,818.38
Median
$3,890.45
Typical High
$6,309.57
Cigna
Setting
Professional
Modifier
Global
Typical Low
$2,041.74
Median
$3,548.13
Typical High
$7,413.10
United
Setting
Facility
Modifier
Global
Typical Low
$3,890.45
Median
$3,890.45
Typical High
$4,466.84
United
Setting
Professional
Modifier
Global
Typical Low
$1,621.81
Median
$2,344.23
Typical High
$4,677.35

Where Indiana sits

The same service costs 3.4 times more in Alaska than in Delaware. Every bar is a state, most expensive first. Touch or drag across it to read any state, then open that state for its carriers and full range.

Indiana· 41st of 51

$3,162

AK $8,710DE $2,570

Median negotiated rate in each state, from every insurer that publishes one. States where no insurer publishes a rate for this service are not shown.