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Breast Cancer Gene Activity Recurrence Score

Maine rates for HCPCS 81521

A laboratory test on a sample of breast cancer tissue that measures the activity of a panel of genes and combines the results into a score estimating how likely the cancer is to come back elsewhere in the body. The score helps decide whether chemotherapy is likely to add benefit on top of hormone treatment.

Rates data updated October 2026.

How much does Breast Cancer Gene Activity Recurrence Score cost?

$3,162

Typical negotiated rate. In Maine, October 2026.

Insurers have agreed to pay about $3,162 for this service. Most negotiated rates run $1,995 to $4,677.

These are rates insurers have negotiated with providers, not the amount a patient is billed. What you owe depends on your plan's deductible and coinsurance. Based on rates published by 6 insurance carriers under federal price transparency rules.

How much rates vary

Facilitymedian $5,129 · 10th to 90th $3,715 to $23,442Professionalmedian $2,344 · 10th to 90th $1,549 to $4,169
$2K$5K$10K$20Kfacility $5,129professional $2,344

Distribution of negotiated rates across all payers (price axis is log-scale). Need provider-level prices or 24+ months of history? Contact us.

Rates by insurance carrier

Insurance Carrier
Aetna
Setting
Professional
Modifier
None
Typical Low
$2,089.30
Median
$3,162.28
Typical High
$3,162.28
Anthem BCBS
Setting
Facility
Modifier
None
Typical Low
$3,715.35
Median
$5,128.61
Typical High
$23,442.29
Anthem BCBS
Setting
Professional
Modifier
None
Typical Low
$1,318.26
Median
$1,905.46
Typical High
$2,511.89
Cigna
Setting
Facility
Modifier
None
Typical Low
$6,165.95
Median
$6,165.95
Typical High
$8,709.64
Cigna
Setting
Professional
Modifier
None
Typical Low
$3,162.28
Median
$3,890.45
Typical High
$4,168.69
Harvard Pilgrim
Setting
Professional
Modifier
None
Typical Low
$2,344.23
Median
$3,890.45
Typical High
$6,760.83
Martin's Point
Setting
Professional
Modifier
None
Typical Low
$3,162.28
Median
$3,162.28
Typical High
$3,162.28
United
Setting
Professional
Modifier
None
Typical Low
$2,344.23
Median
$2,344.23
Typical High
$6,760.83

Where Maine sits

The same service costs 5.4 times more in Alaska than in Alabama. Every bar is a state, most expensive first. Touch or drag across it to read any state, then open that state for its carriers and full range.

Maine· 38th of 51

$3,162

AK $8,710AL $1,622

Median negotiated rate in each state, from every insurer that publishes one. States where no insurer publishes a rate for this service are not shown.