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Breast Cancer Gene Activity Recurrence Score

Alabama rates for HCPCS 81521

A laboratory test on a sample of breast cancer tissue that measures the activity of a panel of genes and combines the results into a score estimating how likely the cancer is to come back elsewhere in the body. The score helps decide whether chemotherapy is likely to add benefit on top of hormone treatment.

Rates data updated July 2026.

How much does Breast Cancer Gene Activity Recurrence Score cost?

$3,020

Typical negotiated rate. In Alabama, July 2026.

Insurers have agreed to pay about $3,020 for this service. The price depends on where it is billed: about $3,020 from a physician practice, and about $3,162 from a hospital or other facility. The two figures are alternatives, not parts of one bill.

These are rates insurers have negotiated with providers, not the amount a patient is billed. What you owe depends on your plan's deductible and coinsurance. Based on rates published by 4 insurance carriers under federal price transparency rules.

Where it's billed changes the price

Billed byTypicalRange
Physician practiceA doctor's office, clinic or independent provider$3,020$2,344 to $4,467
FacilityA hospital or hospital-owned outpatient department$3,162$692 to $4,467

How much rates vary

Facilitymedian $3,162 · 10th to 90th $603 to $4,467Professionalmedian $3,020 · 10th to 90th $2,344 to $4,467
$500.0$1.0K$2.0K$5.0K$10.0K$20.0Kfacility $3,162professional $3,020

Distribution of negotiated rates across all payers (price axis is log-scale). Each curve is scaled to its own total: facility and professional rates are different services, shown together to compare where they cluster. Need provider-level prices or 24+ months of history? Contact us.

Rates by insurance carrier

Insurance Carrier
Aetna
Setting
Facility
Modifier
Global
Typical Low
$3,890.45
Median
$4,466.84
Typical High
$6,025.60
Aetna
Setting
Professional
Modifier
Global
Typical Low
$2,344.23
Median
$3,019.95
Typical High
$4,466.84
BCBS
Setting
Facility
Modifier
Global
Typical Low
$549.54
Median
$660.69
Typical High
$891.25
BCBS
Setting
Professional
Modifier
Global
Typical Low
$2,137.96
Median
$2,511.89
Typical High
$3,311.31
Cigna
Setting
Facility
Modifier
Global
Typical Low
$2,454.71
Median
$3,235.94
Typical High
$6,606.93
Cigna
Setting
Professional
Modifier
Global
Typical Low
$1,479.11
Median
$1,737.80
Typical High
$4,897.79
United
Setting
Facility
Modifier
Global
Typical Low
$1,621.81
Median
$3,467.37
Typical High
$3,890.45
United
Setting
Professional
Modifier
Global
Typical Low
$1,621.81
Median
$1,621.81
Typical High
$3,890.45

Where Alabama sits

The same service costs 3.4 times more in Alaska than in Delaware. Every bar is a state, most expensive first. Pick one to see its carriers and full range.

Alabama $3,020 · 45th of 51
AK $8,710DE $2,570

Median negotiated rate in each state, from every insurer that publishes one. States where no insurer publishes a rate for this service are not shown.