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Gene Activity Test To Find A Tumor's Origin

Nebraska rates for HCPCS 81504

A laboratory test on a tumor sample that compares the activity pattern of its genes against the patterns typical of many known cancer types. It is used when a cancer has been found but the organ it started in is unclear, and it reports how closely the tumor resembles each candidate origin so treatment can be aimed correctly.

Rates data updated October 2026.

How much does Gene Activity Test To Find A Tumor's Origin cost?

$347

Typical negotiated rate. In Nebraska, October 2026.

Insurers have agreed to pay about $347 for this service. The price depends on where it is billed: about $309 from a physician practice, and about $603 from a hospital or other facility.

These are rates insurers have negotiated with providers, not the amount a patient is billed. What you owe depends on your plan's deductible and coinsurance. Based on rates published by 6 insurance carriers under federal price transparency rules.

Prices by location type

Billed byTypicalRange
Physician practiceA doctor's office, clinic or independent provider$309$309 to $977
FacilityA hospital or hospital-owned outpatient department$603$447 to $912

How much rates vary

Facilitymedian $603 · 10th to 90th $309 to $1,259Professionalmedian $309 · 10th to 90th $295 to $2,570
$200$500$1K$2Kfacility $603professional $309

Distribution of negotiated rates across all payers (price axis is log-scale). Need provider-level prices or 24+ months of history? Contact us.

Rates by insurance carrier

Insurance Carrier
Aetna
Setting
Facility
Modifier
None
Typical Low
$346.74
Median
$1,230.27
Typical High
$2,570.40
Aetna
Setting
Professional
Modifier
None
Typical Low
$346.74
Median
$346.74
Typical High
$1,230.27
BCBS Nebraska
Setting
Facility
Modifier
None
Typical Low
$446.68
Median
$602.56
Typical High
$1,202.26
Cigna
Setting
Professional
Modifier
None
Typical Low
$954.99
Median
$977.24
Typical High
$1,258.93
Medica
Setting
Facility
Modifier
None
Typical Low
$186.21
Median
$645.65
Typical High
$2,454.71
Medica
Setting
Professional
Modifier
None
Typical Low
$309.03
Median
$309.03
Typical High
$2,570.40
Midlands
Setting
Professional
Modifier
None
Typical Low
$954.99
Median
$954.99
Typical High
$954.99
Midlands
Setting
Professional
Modifier
None
Typical Low
$954.99
Median
$954.99
Typical High
$954.99
United
Setting
Facility
Modifier
None
Typical Low
$186.21
Median
$218.78
Typical High
$309.03
United
Setting
Professional
Modifier
None
Typical Low
$295.12
Median
$309.03
Typical High
$1,548.82

Where Nebraska sits

The same service costs 8.1 times more in Texas than in Georgia. Every bar is a state, most expensive first. Touch or drag across it to read any state, then open that state for its carriers and full range.

Nebraska· 43rd of 51

$347

TX $1,905GA $234

Median negotiated rate in each state, from every insurer that publishes one. States where no insurer publishes a rate for this service are not shown.