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Gene Activity Test To Find A Tumor's Origin

Maryland rates for HCPCS 81504

A laboratory test on a tumor sample that compares the activity pattern of its genes against the patterns typical of many known cancer types. It is used when a cancer has been found but the organ it started in is unclear, and it reports how closely the tumor resembles each candidate origin so treatment can be aimed correctly.

Rates data updated July 2026.

How much does Gene Activity Test To Find A Tumor's Origin cost?

$389

Typical negotiated rate. In Maryland, July 2026.

Insurers have agreed to pay about $389 for this service. Most negotiated rates run $355 to $447.

These are rates insurers have negotiated with providers, not the amount a patient is billed. What you owe depends on your plan's deductible and coinsurance. Based on rates published by 6 insurance carriers under federal price transparency rules.

How much rates vary

Facilitymedian $219 · 10th to 90th $219 to $398Professionalmedian $389 · 10th to 90th $234 to $646
$200$500$1K$2Kfacility $219professional $389

Distribution of negotiated rates across all payers (price axis is log-scale). Each curve is scaled to its own total: facility and professional rates are different services, shown together to compare where they cluster. Small sample; interpret with caution. Need provider-level prices or 24+ months of history? Contact us.

Rates by insurance carrier

Insurance Carrier
Aetna
Setting
Professional
Modifier
Global
Typical Low
$389.05
Median
$426.58
Typical High
$3,467.37
CareFirst
Setting
Professional
Modifier
Global
Typical Low
$371.54
Median
$371.54
Typical High
$467.74
Cigna
Setting
Professional
Modifier
Global
Typical Low
$281.84
Median
$338.84
Typical High
$1,288.25
Kaiser Permanente
Setting
Professional
Modifier
Global
Typical Low
$524.81
Median
$630.96
Typical High
$776.25
United
Setting
Facility
Modifier
Global
Typical Low
$218.78
Median
$218.78
Typical High
$398.11
United
Setting
Professional
Modifier
Global
Typical Low
$218.78
Median
$234.42
Typical High
$457.09
Wellpoint
Setting
Professional
Modifier
Global
Typical Low
$257.04
Median
$257.04
Typical High
$257.04

Where Maryland sits

The same service costs 3.8 times more in Alaska than in California. Every bar is a state, most expensive first. Touch or drag across it to read any state, then open that state for its carriers and full range.

Maryland· 46th of 51

$389

AK $1,175CA $309

Median negotiated rate in each state, from every insurer that publishes one. States where no insurer publishes a rate for this service are not shown.