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Carrier Screening For Severe Inherited Conditions

Missouri rates for HCPCS 81443

This is a laboratory analysis of a blood or saliva sample that checks a person's DNA for changes linked to a group of serious inherited conditions, such as cystic fibrosis or certain inherited blood disorders. It looks across many genes at once rather than testing for a single condition, and is typically ordered before or during pregnancy to help a couple understand their chance of having a child affected by one of these conditions. Results are usually reviewed with a genetic counselor or physician.

Rates data updated October 2026.

How much does Carrier Screening For Severe Inherited Conditions cost?

$2,239

Typical negotiated rate. In Missouri, October 2026.

Insurers have agreed to pay about $2,239 for this service. The price depends on where it is billed: about $2,089 from a physician practice, and about $4,266 from a hospital or other facility.

These are rates insurers have negotiated with providers, not the amount a patient is billed. What you owe depends on your plan's deductible and coinsurance. Based on rates published by 6 insurance carriers under federal price transparency rules.

Prices by location type

Billed byTypicalRange
Physician practiceA doctor's office, clinic or independent provider$2,089$1,479 to $3,467
FacilityA hospital or hospital-owned outpatient department$4,266$2,512 to $6,310

How much rates vary

Facilitymedian $4,266 · 10th to 90th $2,239 to $11,749Professionalmedian $2,089 · 10th to 90th $1,023 to $6,166
$1K$2K$5K$10K$20Kfacility $4,266professional $2,089

Distribution of negotiated rates across all payers (price axis is log-scale). Need provider-level prices or 24+ months of history? Contact us.

Rates by insurance carrier

Insurance Carrier
Aetna
Setting
Facility
Modifier
None
Typical Low
$2,089.30
Median
$3,162.28
Typical High
$4,466.84
Aetna
Setting
Professional
Modifier
None
Typical Low
$954.99
Median
$2,089.30
Typical High
$2,570.40
Anthem BCBS
Setting
Facility
Modifier
None
Typical Low
$2,454.71
Median
$2,454.71
Typical High
$11,220.18
Anthem BCBS
Setting
Professional
Modifier
None
Typical Low
$977.24
Median
$1,862.09
Typical High
$4,466.84
BCBS Kansas City
Setting
Facility
Modifier
None
Typical Low
$3,388.44
Median
$3,801.89
Typical High
$6,760.83
BCBS Kansas City
Setting
Professional
Modifier
None
Typical Low
$1,698.24
Median
$2,454.71
Typical High
$4,677.35
Cigna
Setting
Facility
Modifier
None
Typical Low
$2,511.89
Median
$5,370.32
Typical High
$12,589.25
Cigna
Setting
Professional
Modifier
None
Typical Low
$1,047.13
Median
$1,905.46
Typical High
$3,162.28
Medica
Setting
Facility
Modifier
None
Typical Low
$2,187.76
Median
$4,265.80
Typical High
$11,748.98
Medica
Setting
Professional
Modifier
None
Typical Low
$1,230.27
Median
$2,570.40
Typical High
$12,302.69
United
Setting
Facility
Modifier
None
Typical Low
$2,187.76
Median
$2,187.76
Typical High
$2,187.76
United
Setting
Professional
Modifier
None
Typical Low
$1,023.29
Median
$1,479.11
Typical High
$3,311.31
2 more rates with less common billing modifiers

A modifier changes what was billed, for example a reduced or repeated service. Each of these modifiers carries under 10% of the published rates for this code. Modifier combinations, and modifiers with fewer than 30 rates for a carrier, are not listed.

Insurance Carrier
Aetna
Setting
Professional
Modifier
52 · Reduced service
Typical Low
$1,047.13
Median
$1,047.13
Typical High
$1,412.54
Aetna
Setting
Professional
Modifier
53 · Discontinued
Typical Low
$416.87
Median
$416.87
Typical High
$562.34

Where Missouri sits

The same service costs 5.4 times more in Alaska than in Alabama. Every bar is a state, most expensive first. Touch or drag across it to read any state, then open that state for its carriers and full range.

Missouri· 27th of 51

$2,239

AK $5,495AL $1,023

Median negotiated rate in each state, from every insurer that publishes one. States where no insurer publishes a rate for this service are not shown.