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Carrier Screening For Severe Inherited Conditions

Massachusetts rates for HCPCS 81443

This is a laboratory analysis of a blood or saliva sample that checks a person's DNA for changes linked to a group of serious inherited conditions, such as cystic fibrosis or certain inherited blood disorders. It looks across many genes at once rather than testing for a single condition, and is typically ordered before or during pregnancy to help a couple understand their chance of having a child affected by one of these conditions. Results are usually reviewed with a genetic counselor or physician.

Rates data updated October 2026.

How much does Carrier Screening For Severe Inherited Conditions cost?

$2,455

Typical negotiated rate. In Massachusetts, October 2026.

Insurers have agreed to pay about $2,455 for this service. The price depends on where it is billed: about $2,455 from a physician practice, and about $3,090 from a hospital or other facility.

These are rates insurers have negotiated with providers, not the amount a patient is billed. What you owe depends on your plan's deductible and coinsurance. Based on rates published by 10 insurance carriers under federal price transparency rules.

Prices by location type

Billed byTypicalRange
Physician practiceA doctor's office, clinic or independent provider$2,455$1,479 to $6,166
FacilityA hospital or hospital-owned outpatient department$3,090$2,455 to $4,365

How much rates vary

Facilitymedian $3,090 · 10th to 90th $1,820 to $7,079Professionalmedian $2,455 · 10th to 90th $1,479 to $12,303
$100$200$500$1K$2K$5K$10Kfacility $3,090professional $2,455

Distribution of negotiated rates across all payers (price axis is log-scale). Need provider-level prices or 24+ months of history? Contact us.

Rates by insurance carrier

Insurance Carrier
Aetna
Setting
Facility
Modifier
None
Typical Low
$1,698.24
Median
$3,467.37
Typical High
$7,585.78
Aetna
Setting
Professional
Modifier
None
Typical Low
$1,698.24
Median
$1,698.24
Typical High
$1,698.24
AllWays Health Partners
Setting
Facility
Modifier
None
Typical Low
$1,819.70
Median
$2,818.38
Typical High
$7,413.10
AllWays Health Partners
Setting
Professional
Modifier
None
Typical Low
$1,479.11
Median
$4,897.79
Typical High
$12,302.69
BCBS Massachusetts
Setting
Facility
Modifier
None
Typical Low
$2,454.71
Median
$3,090.30
Typical High
$6,165.95
BCBS Massachusetts
Setting
Professional
Modifier
None
Typical Low
$2,290.87
Median
$2,290.87
Typical High
$2,290.87
Cigna
Setting
Facility
Modifier
None
Typical Low
$1,621.81
Median
$1,905.46
Typical High
$4,365.16
Cigna
Setting
Professional
Modifier
None
Typical Low
$1,318.26
Median
$2,630.27
Typical High
$9,549.93
Fallon Health
Setting
Facility
Modifier
None
Typical Low
$1,288.25
Median
$3,630.78
Typical High
$8,511.38
Fallon Health
Setting
Professional
Modifier
None
Typical Low
$3,467.37
Median
$3,467.37
Typical High
$4,168.69
Harvard Pilgrim
Setting
Professional
Modifier
None
Typical Low
$1,023.29
Median
$2,454.71
Typical High
$6,309.57
Health New England
Setting
Facility
Modifier
None
Typical Low
$1,513.56
Median
$1,862.09
Typical High
$3,890.45
Mass General Brigham
Setting
Facility
Modifier
None
Typical Low
$1,819.70
Median
$2,818.38
Typical High
$7,413.10
Mass General Brigham
Setting
Professional
Modifier
None
Typical Low
$1,479.11
Median
$4,897.79
Typical High
$12,302.69
United
Setting
Facility
Modifier
None
Typical Low
$2,187.76
Median
$2,454.71
Typical High
$2,951.21
United
Setting
Professional
Modifier
None
Typical Low
$977.24
Median
$1,479.11
Typical High
$4,677.35
Well Sense
Setting
Facility
Modifier
None
Typical Low
$2,137.96
Median
$3,019.95
Typical High
$4,466.84
Well Sense
Setting
Professional
Modifier
None
Typical Low
$2,511.89
Median
$2,511.89
Typical High
$3,019.95
3 more rates with less common billing modifiers

A modifier changes what was billed, for example a reduced or repeated service. Each of these modifiers carries under 10% of the published rates for this code. Modifier combinations, and modifiers with fewer than 30 rates for a carrier, are not listed.

Insurance Carrier
Aetna
Setting
Professional
Modifier
52 · Reduced service
Typical Low
$851.14
Median
$851.14
Typical High
$851.14
Aetna
Setting
Professional
Modifier
53 · Discontinued
Typical Low
$346.74
Median
$346.74
Typical High
$346.74
Fallon Health
Setting
Facility
Modifier
QW · Waived lab test
Typical Low
$2,454.71
Median
$3,162.28
Typical High
$3,801.89

Where Massachusetts sits

The same service costs 5.4 times more in Alaska than in Alabama. Every bar is a state, most expensive first. Touch or drag across it to read any state, then open that state for its carriers and full range.

Massachusetts· 19th of 51

$2,455

AK $5,495AL $1,023

Median negotiated rate in each state, from every insurer that publishes one. States where no insurer publishes a rate for this service are not shown.