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Whole Genome Sequencing For An Unexplained Condition

Alabama rates for HCPCS 81425

Reads essentially all of a person's DNA in one test, looking for the change behind an unexplained condition that may have been present from birth or that runs in the family. It goes wider than tests that read only the protein-coding stretches of the genes, which are a separate service. Results take weeks, and findings unrelated to the original question can turn up.

Rates data updated October 2026.

How much does Whole Genome Sequencing For An Unexplained Condition cost?

$589

Typical facility fee. In Alabama, October 2026.

Insurers have agreed to pay about $589 for this service. Most negotiated rates run $589 to $2,754.

These are rates insurers have negotiated with providers, not the amount a patient is billed. What you owe depends on your plan's deductible and coinsurance. Based on rates published by 3 insurance carriers under federal price transparency rules.

How much rates vary

Facilitymedian $589 · 10th to 90th $589 to $4,074Professionalmedian $2,512 · 10th to 90th $2,089 to $3,020
$1K$2K$5K$10Kfacility $589professional $2,512

Distribution of negotiated rates across all payers (price axis is log-scale). Need provider-level prices or 24+ months of history? Contact us.

Rates by insurance carrier

Insurance Carrier
BCBS Alabama
Setting
Facility
Modifier
None
Typical Low
$588.84
Median
$588.84
Typical High
$588.84
BCBS Alabama
Setting
Professional
Modifier
21 + 22 · Increased work + 24 · Unrelated visit after surgery + 31
Typical Low
$354.81
Median
$512.86
Typical High
$512.86
Cigna
Setting
Facility
Modifier
None
Typical Low
$3,235.94
Median
$4,073.80
Typical High
$10,964.78
Cigna
Setting
Professional
Modifier
None
Typical Low
$2,187.76
Median
$2,290.87
Typical High
$7,762.47
United
Setting
Facility
Modifier
None
Typical Low
$1,819.70
Median
$4,570.88
Typical High
$5,011.87
United
Setting
Professional
Modifier
None
Typical Low
$2,089.30
Median
$2,754.23
Typical High
$3,019.95

Where Alabama sits

The same service costs 30.9 times more in Texas than in Alabama. Every bar is a state, most expensive first. Touch or drag across it to read any state, then open that state for its carriers and full range.

Alabama· 51st of 51

$589

TX $18,197AL $589

Median negotiated rate in each state, from every insurer that publishes one. States where no insurer publishes a rate for this service are not shown.