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Prenatal Blood Test For Chromosomal Deletions

South Carolina rates for HCPCS 81422

This service is a blood test done during pregnancy that analyzes small fragments of the baby's DNA circulating in the mother's bloodstream to screen for specific chromosomal deletion syndromes - conditions caused by a missing piece of a chromosome that can be linked to birth defects or developmental conditions. It is a noninvasive screening test, meaning it does not carry the risks associated with procedures like amniocentesis. A positive result is typically followed up with further diagnostic testing.

Rates data updated October 2026.

How much does Prenatal Blood Test For Chromosomal Deletions cost?

$589

Typical negotiated rate. In South Carolina, October 2026.

Insurers have agreed to pay about $589 for this service. The price depends on where it is billed: about $589 from a physician practice, and about $1,445 from a hospital or other facility.

These are rates insurers have negotiated with providers, not the amount a patient is billed. What you owe depends on your plan's deductible and coinsurance. Based on rates published by 5 insurance carriers under federal price transparency rules.

Prices by location type

Billed byTypicalRange
Physician practiceA doctor's office, clinic or independent provider$589$490 to $759
FacilityA hospital or hospital-owned outpatient department$1,445$708 to $3,090

How much rates vary

Facilitymedian $1,445 · 10th to 90th $589 to $4,677Professionalmedian $589 · 10th to 90th $372 to $871
$500$1K$2K$5Kfacility $1,445professional $589

Distribution of negotiated rates across all payers (price axis is log-scale). Small sample; interpret with caution. Need provider-level prices or 24+ months of history? Contact us.

Rates by insurance carrier

Insurance Carrier
Aetna
Setting
Facility
Modifier
None
Typical Low
$588.84
Median
$588.84
Typical High
$588.84
Aetna
Setting
Professional
Modifier
None
Typical Low
$588.84
Median
$588.84
Typical High
$602.56
BCBS South Carolina
Setting
Facility
Modifier
None
Typical Low
$4,073.80
Median
$4,073.80
Typical High
$4,168.69
BCBS South Carolina
Setting
Professional
Modifier
None
Typical Low
$489.78
Median
$630.96
Typical High
$870.96
Cigna
Setting
Facility
Modifier
None
Typical Low
$1,445.44
Median
$1,905.46
Typical High
$4,677.35
Cigna
Setting
Professional
Modifier
None
Typical Low
$346.74
Median
$380.19
Typical High
$912.01
Medcost
Setting
Facility
Modifier
None
Typical Low
$537.03
Median
$707.95
Typical High
$1,000.00
Medcost
Setting
Professional
Modifier
None
Typical Low
$794.33
Median
$794.33
Typical High
$1,071.52
United
Setting
Facility
Modifier
None
Typical Low
$676.08
Median
$676.08
Typical High
$912.01
United
Setting
Professional
Modifier
None
Typical Low
$316.23
Median
$457.09
Typical High
$794.33
3 more rates with less common billing modifiers

A modifier changes what was billed, for example a reduced or repeated service. Each of these modifiers carries under 10% of the published rates for this code. Modifier combinations, and modifiers with fewer than 30 rates for a carrier, are not listed.

Insurance Carrier
Aetna
Setting
Professional
Modifier
52 · Reduced service
Typical Low
$295.12
Median
$295.12
Typical High
$302.00
Aetna
Setting
Professional
Modifier
53 · Discontinued
Typical Low
$117.49
Median
$117.49
Typical High
$120.23
Medcost
Setting
Professional
Modifier
51 · Multiple procedures
Typical Low
$398.11
Median
$398.11
Typical High
$645.65

Where South Carolina sits

The same service costs 4.0 times more in Alaska than in Oklahoma. Every bar is a state, most expensive first. Touch or drag across it to read any state, then open that state for its carriers and full range.

South Carolina· 35th of 51

$589

AK $1,698OK $427

Median negotiated rate in each state, from every insurer that publishes one. States where no insurer publishes a rate for this service are not shown.