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Prenatal Blood Test For Chromosomal Deletions

North Carolina rates for HCPCS 81422

This service is a blood test done during pregnancy that analyzes small fragments of the baby's DNA circulating in the mother's bloodstream to screen for specific chromosomal deletion syndromes - conditions caused by a missing piece of a chromosome that can be linked to birth defects or developmental conditions. It is a noninvasive screening test, meaning it does not carry the risks associated with procedures like amniocentesis. A positive result is typically followed up with further diagnostic testing.

Rates data updated October 2026.

How much does Prenatal Blood Test For Chromosomal Deletions cost?

$741

Typical negotiated rate. In North Carolina, October 2026.

Insurers have agreed to pay about $741 for this service. The price depends on where it is billed: about $759 from a physician practice, and about $631 from a hospital or other facility.

These are rates insurers have negotiated with providers, not the amount a patient is billed. What you owe depends on your plan's deductible and coinsurance. Based on rates published by 6 insurance carriers under federal price transparency rules.

Prices by location type

Billed byTypicalRange
Physician practiceA doctor's office, clinic or independent provider$759$525 to $1,072
FacilityA hospital or hospital-owned outpatient department$631$603 to $1,660

How much rates vary

Facilitymedian $631 · 10th to 90th $513 to $3,467Professionalmedian $759 · 10th to 90th $380 to $1,995
$500$1K$2Kfacility $631professional $759

Distribution of negotiated rates across all payers (price axis is log-scale). Need provider-level prices or 24+ months of history? Contact us.

Rates by insurance carrier

Insurance Carrier
Aetna
Setting
Facility
Modifier
None
Typical Low
$602.56
Median
$602.56
Typical High
$602.56
Aetna
Setting
Professional
Modifier
None
Typical Low
$549.54
Median
$602.56
Typical High
$660.69
BCBS North Carolina
Setting
Facility
Modifier
None
Typical Low
$1,698.24
Median
$2,137.96
Typical High
$2,398.83
BCBS North Carolina
Setting
Professional
Modifier
None
Typical Low
$676.08
Median
$831.76
Typical High
$2,398.83
Cigna
Setting
Facility
Modifier
None
Typical Low
$512.86
Median
$1,659.59
Typical High
$3,467.37
Cigna
Setting
Professional
Modifier
None
Typical Low
$354.81
Median
$457.09
Typical High
$1,148.15
Medcost
Setting
Professional
Modifier
None
Typical Low
$794.33
Median
$794.33
Typical High
$794.33
Medcost
Setting
Facility
Modifier
None
Typical Low
$457.09
Median
$602.56
Typical High
$794.33
Medcost
Setting
Professional
Modifier
None
Typical Low
$741.31
Median
$794.33
Typical High
$1,318.26
United
Setting
Professional
Modifier
None
Typical Low
$316.23
Median
$398.11
Typical High
$794.33
4 more rates with less common billing modifiers

A modifier changes what was billed, for example a reduced or repeated service. Each of these modifiers carries under 10% of the published rates for this code. Modifier combinations, and modifiers with fewer than 30 rates for a carrier, are not listed.

Insurance Carrier
Aetna
Setting
Professional
Modifier
52 · Reduced service
Typical Low
$302.00
Median
$302.00
Typical High
$331.13
Aetna
Setting
Professional
Modifier
53 · Discontinued
Typical Low
$120.23
Median
$120.23
Typical High
$131.83
Ambetter
Setting
Professional
Modifier
90 · Outside lab
Typical Low
$478.63
Median
$478.63
Typical High
$478.63
Medcost
Setting
Professional
Modifier
51 · Multiple procedures
Typical Low
$398.11
Median
$398.11
Typical High
$1,047.13

Where North Carolina sits

The same service costs 4.0 times more in Alaska than in Oklahoma. Every bar is a state, most expensive first. Touch or drag across it to read any state, then open that state for its carriers and full range.

North Carolina· 22nd of 51

$741

AK $1,698OK $427

Median negotiated rate in each state, from every insurer that publishes one. States where no insurer publishes a rate for this service are not shown.