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Prenatal Blood Test For Chromosomal Deletions

Missouri rates for HCPCS 81422

This service is a blood test done during pregnancy that analyzes small fragments of the baby's DNA circulating in the mother's bloodstream to screen for specific chromosomal deletion syndromes - conditions caused by a missing piece of a chromosome that can be linked to birth defects or developmental conditions. It is a noninvasive screening test, meaning it does not carry the risks associated with procedures like amniocentesis. A positive result is typically followed up with further diagnostic testing.

Rates data updated October 2026.

How much does Prenatal Blood Test For Chromosomal Deletions cost?

$646

Typical negotiated rate. In Missouri, October 2026.

Insurers have agreed to pay about $646 for this service. The price depends on where it is billed: about $562 from a physician practice, and about $1,318 from a hospital or other facility.

These are rates insurers have negotiated with providers, not the amount a patient is billed. What you owe depends on your plan's deductible and coinsurance. Based on rates published by 6 insurance carriers under federal price transparency rules.

Prices by location type

Billed byTypicalRange
Physician practiceA doctor's office, clinic or independent provider$562$457 to $1,000
FacilityA hospital or hospital-owned outpatient department$1,318$759 to $2,630

How much rates vary

Facilitymedian $1,318 · 10th to 90th $646 to $3,631Professionalmedian $562 · 10th to 90th $324 to $1,905
$500$1K$2K$5Kfacility $1,318professional $562

Distribution of negotiated rates across all payers (price axis is log-scale). Need provider-level prices or 24+ months of history? Contact us.

Rates by insurance carrier

Insurance Carrier
Aetna
Setting
Facility
Modifier
None
Typical Low
$645.65
Median
$977.24
Typical High
$1,412.54
Aetna
Setting
Professional
Modifier
None
Typical Low
$588.84
Median
$645.65
Typical High
$870.96
Anthem BCBS
Setting
Facility
Modifier
None
Typical Low
$758.58
Median
$758.58
Typical High
$3,467.37
Anthem BCBS
Setting
Professional
Modifier
None
Typical Low
$302.00
Median
$478.63
Typical High
$1,380.38
BCBS Kansas City
Setting
Facility
Modifier
None
Typical Low
$1,122.02
Median
$1,148.15
Typical High
$2,187.76
BCBS Kansas City
Setting
Professional
Modifier
None
Typical Low
$537.03
Median
$794.33
Typical High
$1,445.44
Cigna
Setting
Facility
Modifier
None
Typical Low
$562.34
Median
$1,659.59
Typical High
$3,311.31
Cigna
Setting
Professional
Modifier
None
Typical Low
$338.84
Median
$724.44
Typical High
$1,096.48
Medica
Setting
Facility
Modifier
None
Typical Low
$660.69
Median
$1,318.26
Typical High
$3,630.78
Medica
Setting
Professional
Modifier
None
Typical Low
$380.19
Median
$794.33
Typical High
$3,801.89
United
Setting
Facility
Modifier
None
Typical Low
$676.08
Median
$676.08
Typical High
$676.08
United
Setting
Professional
Modifier
None
Typical Low
$316.23
Median
$457.09
Typical High
$1,023.29
2 more rates with less common billing modifiers

A modifier changes what was billed, for example a reduced or repeated service. Each of these modifiers carries under 10% of the published rates for this code. Modifier combinations, and modifiers with fewer than 30 rates for a carrier, are not listed.

Insurance Carrier
Aetna
Setting
Professional
Modifier
52 · Reduced service
Typical Low
$323.59
Median
$323.59
Typical High
$436.52
Aetna
Setting
Professional
Modifier
53 · Discontinued
Typical Low
$128.82
Median
$131.83
Typical High
$173.78

Where Missouri sits

The same service costs 4.0 times more in Alaska than in Oklahoma. Every bar is a state, most expensive first. Touch or drag across it to read any state, then open that state for its carriers and full range.

Missouri· 31st of 51

$646

AK $1,698OK $427

Median negotiated rate in each state, from every insurer that publishes one. States where no insurer publishes a rate for this service are not shown.