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Prenatal Blood Test For Chromosomal Deletions

Maryland rates for HCPCS 81422

This service is a blood test done during pregnancy that analyzes small fragments of the baby's DNA circulating in the mother's bloodstream to screen for specific chromosomal deletion syndromes - conditions caused by a missing piece of a chromosome that can be linked to birth defects or developmental conditions. It is a noninvasive screening test, meaning it does not carry the risks associated with procedures like amniocentesis. A positive result is typically followed up with further diagnostic testing.

Rates data updated October 2026.

How much does Prenatal Blood Test For Chromosomal Deletions cost?

$575

Typical negotiated rate. In Maryland, October 2026.

Insurers have agreed to pay about $575 for this service. Most negotiated rates run $501 to $603.

These are rates insurers have negotiated with providers, not the amount a patient is billed. What you owe depends on your plan's deductible and coinsurance. Based on rates published by 6 insurance carriers under federal price transparency rules.

How much rates vary

Facilitymedian $398 · 10th to 90th $389 to $708Professionalmedian $575 · 10th to 90th $339 to $759
$500$1Kfacility $398professional $575

Distribution of negotiated rates across all payers (price axis is log-scale). Small sample; interpret with caution. Need provider-level prices or 24+ months of history? Contact us.

Rates by insurance carrier

Insurance Carrier
Aetna
Setting
Professional
Modifier
None
Typical Low
$562.34
Median
$575.44
Typical High
$616.60
CareFirst
Setting
Professional
Modifier
None
Typical Low
$549.54
Median
$602.56
Typical High
$602.56
Cigna
Setting
Facility
Modifier
None
Typical Low
$389.05
Median
$398.11
Typical High
$707.95
Cigna
Setting
Professional
Modifier
None
Typical Low
$398.11
Median
$724.44
Typical High
$1,862.09
Kaiser Permanente
Setting
Professional
Modifier
None
Typical Low
$758.58
Median
$912.01
Typical High
$1,148.15
United
Setting
Professional
Modifier
None
Typical Low
$323.59
Median
$380.19
Typical High
$660.69
Wellpoint
Setting
Professional
Modifier
None
Typical Low
$302.00
Median
$602.56
Typical High
$602.56
2 more rates with less common billing modifiers

A modifier changes what was billed, for example a reduced or repeated service. Each of these modifiers carries under 10% of the published rates for this code. Modifier combinations, and modifiers with fewer than 30 rates for a carrier, are not listed.

Insurance Carrier
Aetna
Setting
Professional
Modifier
52 · Reduced service
Typical Low
$281.84
Median
$281.84
Typical High
$309.03
Aetna
Setting
Professional
Modifier
53 · Discontinued
Typical Low
$112.20
Median
$114.82
Typical High
$125.89

Where Maryland sits

The same service costs 4.0 times more in Alaska than in Oklahoma. Every bar is a state, most expensive first. Touch or drag across it to read any state, then open that state for its carriers and full range.

Maryland· 40th of 51

$575

AK $1,698OK $427

Median negotiated rate in each state, from every insurer that publishes one. States where no insurer publishes a rate for this service are not shown.