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Prenatal Blood Test For Chromosomal Deletions

Massachusetts rates for HCPCS 81422

This service is a blood test done during pregnancy that analyzes small fragments of the baby's DNA circulating in the mother's bloodstream to screen for specific chromosomal deletion syndromes - conditions caused by a missing piece of a chromosome that can be linked to birth defects or developmental conditions. It is a noninvasive screening test, meaning it does not carry the risks associated with procedures like amniocentesis. A positive result is typically followed up with further diagnostic testing.

Rates data updated October 2026.

How much does Prenatal Blood Test For Chromosomal Deletions cost?

$794

Typical negotiated rate. In Massachusetts, October 2026.

Insurers have agreed to pay about $794 for this service. The price depends on where it is billed: about $759 from a physician practice, and about $1,047 from a hospital or other facility.

These are rates insurers have negotiated with providers, not the amount a patient is billed. What you owe depends on your plan's deductible and coinsurance. Based on rates published by 9 insurance carriers under federal price transparency rules.

Prices by location type

Billed byTypicalRange
Physician practiceA doctor's office, clinic or independent provider$759$479 to $1,862
FacilityA hospital or hospital-owned outpatient department$1,047$676 to $1,514

How much rates vary

Facilitymedian $1,047 · 10th to 90th $562 to $2,291Professionalmedian $759 · 10th to 90th $457 to $3,802
$100$200$500$1K$2K$5Kfacility $1,047professional $759

Distribution of negotiated rates across all payers (price axis is log-scale). Need provider-level prices or 24+ months of history? Contact us.

Rates by insurance carrier

Insurance Carrier
Aetna
Setting
Facility
Modifier
None
Typical Low
$562.34
Median
$1,122.02
Typical High
$2,511.89
Aetna
Setting
Professional
Modifier
None
Typical Low
$562.34
Median
$562.34
Typical High
$562.34
AllWays Health Partners
Setting
Facility
Modifier
None
Typical Low
$562.34
Median
$794.33
Typical High
$2,238.72
AllWays Health Partners
Setting
Professional
Modifier
None
Typical Low
$457.09
Median
$1,148.15
Typical High
$3,801.89
BCBS Massachusetts
Setting
Facility
Modifier
None
Typical Low
$1,202.26
Median
$1,698.24
Typical High
$2,454.71
BCBS Massachusetts
Setting
Professional
Modifier
None
Typical Low
$645.65
Median
$645.65
Typical High
$645.65
Cigna
Setting
Facility
Modifier
None
Typical Low
$489.78
Median
$660.69
Typical High
$1,479.11
Cigna
Setting
Professional
Modifier
None
Typical Low
$389.05
Median
$794.33
Typical High
$2,951.21
Fallon Health
Setting
Facility
Modifier
None
Typical Low
$794.33
Median
$1,288.25
Typical High
$5,888.44
Fallon Health
Setting
Professional
Modifier
None
Typical Low
$1,096.48
Median
$1,096.48
Typical High
$1,288.25
Harvard Pilgrim
Setting
Professional
Modifier
None
Typical Low
$457.09
Median
$758.58
Typical High
$1,737.80
Mass General Brigham
Setting
Facility
Modifier
None
Typical Low
$562.34
Median
$794.33
Typical High
$2,238.72
Mass General Brigham
Setting
Professional
Modifier
None
Typical Low
$457.09
Median
$1,148.15
Typical High
$3,801.89
United
Setting
Facility
Modifier
None
Typical Low
$676.08
Median
$758.58
Typical High
$912.01
United
Setting
Professional
Modifier
None
Typical Low
$302.00
Median
$457.09
Typical High
$1,445.44
Well Sense
Setting
Facility
Modifier
None
Typical Low
$602.56
Median
$831.76
Typical High
$1,318.26
Well Sense
Setting
Professional
Modifier
None
Typical Low
$602.56
Median
$602.56
Typical High
$724.44
3 more rates with less common billing modifiers

A modifier changes what was billed, for example a reduced or repeated service. Each of these modifiers carries under 10% of the published rates for this code. Modifier combinations, and modifiers with fewer than 30 rates for a carrier, are not listed.

Insurance Carrier
Aetna
Setting
Professional
Modifier
52 · Reduced service
Typical Low
$281.84
Median
$281.84
Typical High
$281.84
Aetna
Setting
Professional
Modifier
53 · Discontinued
Typical Low
$112.20
Median
$112.20
Typical High
$112.20
Fallon Health
Setting
Facility
Modifier
QW · Waived lab test
Typical Low
$758.58
Median
$977.24
Typical High
$1,174.90

Where Massachusetts sits

The same service costs 4.0 times more in Alaska than in Oklahoma. Every bar is a state, most expensive first. Touch or drag across it to read any state, then open that state for its carriers and full range.

Massachusetts· 16th of 51

$794

AK $1,698OK $427

Median negotiated rate in each state, from every insurer that publishes one. States where no insurer publishes a rate for this service are not shown.