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Prenatal Blood Test For Chromosomal Deletions

Illinois rates for HCPCS 81422

This service is a blood test done during pregnancy that analyzes small fragments of the baby's DNA circulating in the mother's bloodstream to screen for specific chromosomal deletion syndromes - conditions caused by a missing piece of a chromosome that can be linked to birth defects or developmental conditions. It is a noninvasive screening test, meaning it does not carry the risks associated with procedures like amniocentesis. A positive result is typically followed up with further diagnostic testing.

Rates data updated October 2026.

How much does Prenatal Blood Test For Chromosomal Deletions cost?

$589

Typical negotiated rate. In Illinois, October 2026.

Insurers have agreed to pay about $589 for this service. The price depends on where it is billed: about $589 from a physician practice, and about $1,585 from a hospital or other facility.

These are rates insurers have negotiated with providers, not the amount a patient is billed. What you owe depends on your plan's deductible and coinsurance. Based on rates published by 6 insurance carriers under federal price transparency rules.

Prices by location type

Billed byTypicalRange
Physician practiceA doctor's office, clinic or independent provider$589$339 to $589
FacilityA hospital or hospital-owned outpatient department$1,585$1,023 to $2,884

How much rates vary

Facilitymedian $1,585 · 10th to 90th $851 to $5,495Professionalmedian $589 · 10th to 90th $3 to $912
$10$100$1K$10Kfacility $1,585professional $589

Distribution of negotiated rates across all payers (price axis is log-scale). Need provider-level prices or 24+ months of history? Contact us.

Rates by insurance carrier

Insurance Carrier
Aetna
Setting
Facility
Modifier
None
Typical Low
$616.60
Median
$1,202.26
Typical High
$2,290.87
Aetna
Setting
Professional
Modifier
None
Typical Low
$616.60
Median
$616.60
Typical High
$707.95
BCBS Illinois
Setting
Facility
Modifier
None
Typical Low
$912.01
Median
$1,318.26
Typical High
$9,549.93
BCBS Illinois
Setting
Professional
Modifier
None
Typical Low
$3.47
Median
$588.84
Typical High
$588.84
Cigna
Setting
Facility
Modifier
None
Typical Low
$851.14
Median
$1,819.70
Typical High
$3,311.31
Cigna
Setting
Professional
Modifier
None
Typical Low
$363.08
Median
$891.25
Typical High
$1,202.26
Hally Health
Setting
Professional
Modifier
None
Typical Low
$758.58
Median
$1,148.15
Typical High
$1,778.28
Hally Health
Setting
Facility
Modifier
None
Typical Low
$100.00
Median
$100.00
Typical High
$100.00
Hally Health
Setting
Professional
Modifier
None
Typical Low
$977.24
Median
$977.24
Typical High
$977.24
Molina
Setting
Professional
Modifier
None
Typical Low
$416.87
Median
$537.03
Typical High
$954.99
United
Setting
Facility
Modifier
None
Typical Low
$758.58
Median
$912.01
Typical High
$954.99
United
Setting
Professional
Modifier
None
Typical Low
$316.23
Median
$457.09
Typical High
$794.33
4 more rates with less common billing modifiers

A modifier changes what was billed, for example a reduced or repeated service. Each of these modifiers carries under 10% of the published rates for this code. Modifier combinations, and modifiers with fewer than 30 rates for a carrier, are not listed.

Insurance Carrier
Aetna
Setting
Facility
Modifier
52 · Reduced service
Typical Low
$309.03
Median
$588.84
Typical High
$1,148.15
Aetna
Setting
Facility
Modifier
53 · Discontinued
Typical Low
$125.89
Median
$239.88
Typical High
$457.09
Aetna
Setting
Professional
Modifier
52 · Reduced service
Typical Low
$309.03
Median
$309.03
Typical High
$338.84
Aetna
Setting
Professional
Modifier
53 · Discontinued
Typical Low
$125.89
Median
$125.89
Typical High
$138.04

Where Illinois sits

The same service costs 4.0 times more in Alaska than in Oklahoma. Every bar is a state, most expensive first. Touch or drag across it to read any state, then open that state for its carriers and full range.

Illinois· 36th of 51

$589

AK $1,698OK $427

Median negotiated rate in each state, from every insurer that publishes one. States where no insurer publishes a rate for this service are not shown.