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Highly Complex Genetic Laboratory Analysis

South Carolina rates for HCPCS 81407

This represents one of the most technically complex levels of gene-based laboratory analysis available, used when evaluating certain inherited conditions or cancer-related genetic changes that require especially involved laboratory work to identify. The complexity reflects factors such as the size of the genetic region examined and the analytic methods required, rather than testing for one single, simple genetic change. It requires only a blood or tissue sample.

Rates data updated July 2026.

How much does Highly Complex Genetic Laboratory Analysis cost?

$676

Typical negotiated rate. In South Carolina, July 2026.

Insurers have agreed to pay about $676 for this service. The price depends on where it is billed: about $661 from a physician practice, and about $1,585 from a hospital or other facility. The two figures are alternatives, not parts of one bill.

These are rates insurers have negotiated with providers, not the amount a patient is billed. What you owe depends on your plan's deductible and coinsurance. Based on rates published by 5 insurance carriers under federal price transparency rules.

Where it's billed changes the price

Billed byTypicalRange
Physician practiceA doctor's office, clinic or independent provider$661$661 to $692
FacilityA hospital or hospital-owned outpatient department$1,585$661 to $2,692

How much rates vary

Facilitymedian $1,585 · 10th to 90th $661 to $3,981Professionalmedian $661 · 10th to 90th $513 to $891
$500$1K$2K$5Kfacility $1,585professional $661

Distribution of negotiated rates across all payers (price axis is log-scale). Each curve is scaled to its own total: facility and professional rates are different services, shown together to compare where they cluster. Need provider-level prices or 24+ months of history? Contact us.

Rates by insurance carrier

Insurance Carrier
Aetna
Setting
Facility
Modifier
Global
Typical Low
$588.84
Median
$2,089.30
Typical High
$3,981.07
Aetna
Setting
Professional
Modifier
Global
Typical Low
$660.69
Median
$660.69
Typical High
$758.58
BCBS
Setting
Facility
Modifier
Global
Typical Low
$5,248.07
Median
$5,248.07
Typical High
$5,623.41
BCBS
Setting
Professional
Modifier
Global
Typical Low
$269.15
Median
$891.25
Typical High
$1,174.90
Cigna
Setting
Facility
Modifier
Global
Typical Low
$1,584.89
Median
$2,511.89
Typical High
$4,786.30
Cigna
Setting
Professional
Modifier
Global
Typical Low
$380.19
Median
$457.09
Typical High
$1,949.84
Medcost
Setting
Facility
Modifier
Global
Typical Low
$660.69
Median
$794.33
Typical High
$1,202.26
United
Setting
Facility
Modifier
Global
Typical Low
$758.58
Median
$851.14
Typical High
$1,023.29
United
Setting
Professional
Modifier
Global
Typical Low
$354.81
Median
$512.86
Typical High
$851.14

Where South Carolina sits

The same service costs 3.0 times more in Alaska than in Washington, DC. Every bar is a state, most expensive first. Touch or drag across it to read any state, then open that state for its carriers and full range.

South Carolina· 49th of 51

$676

AK $1,905DC $631

Median negotiated rate in each state, from every insurer that publishes one. States where no insurer publishes a rate for this service are not shown.