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Targeted Gene Sequencing Analysis

Massachusetts rates for HCPCS 81405

This laboratory analysis examines the DNA sequence of a specific gene associated with an inherited condition, looking for changes that could explain a patient's symptoms or family history. It is one of many single-gene analyzes available, each ordered based on the particular condition being evaluated. Results help confirm a diagnosis or guide further testing and family counseling.

Rates data updated July 2026.

How much does Targeted Gene Sequencing Analysis cost?

$302

Typical negotiated rate. In Massachusetts, July 2026.

Insurers have agreed to pay about $302 for this service. The price depends on where it is billed: about $302 from a physician practice, and about $603 from a hospital or other facility. The two figures are alternatives, not parts of one bill.

These are rates insurers have negotiated with providers, not the amount a patient is billed. What you owe depends on your plan's deductible and coinsurance. Based on rates published by 8 insurance carriers under federal price transparency rules.

Where it's billed changes the price

Billed byTypicalRange
Physician practiceA doctor's office, clinic or independent provider$302$182 to $302
FacilityA hospital or hospital-owned outpatient department$603$417 to $871

How much rates vary

Facilitymedian $603 · 10th to 90th $302 to $955Professionalmedian $302 · 10th to 90th $174 to $676
$100$200$500$1K$2K$5Kfacility $603professional $302

Distribution of negotiated rates across all payers (price axis is log-scale). Each curve is scaled to its own total: facility and professional rates are different services, shown together to compare where they cluster. Need provider-level prices or 24+ months of history? Contact us.

Rates by insurance carrier

Insurance Carrier
Aetna
Setting
Facility
Modifier
Global
Typical Low
$173.78
Median
$524.81
Typical High
$891.25
Aetna
Setting
Professional
Modifier
Global
Typical Low
$173.78
Median
$173.78
Typical High
$912.01
AllWays Health Partners
Setting
Facility
Modifier
Global
Typical Low
$331.13
Median
$870.96
Typical High
$1,584.89
AllWays Health Partners
Setting
Professional
Modifier
Global
Typical Low
$181.97
Median
$302.00
Typical High
$891.25
BCBS
Setting
Facility
Modifier
Global
Typical Low
$478.63
Median
$602.56
Typical High
$870.96
BCBS
Setting
Professional
Modifier
Global
Typical Low
$77.62
Median
$77.62
Typical High
$77.62
Cigna
Setting
Facility
Modifier
Global
Typical Low
$194.98
Median
$371.54
Typical High
$588.84
Cigna
Setting
Professional
Modifier
Global
Typical Low
$162.18
Median
$316.23
Typical High
$794.33
Fallon Health
Setting
Facility
Modifier
Global
Typical Low
$83.18
Median
$3,630.78
Typical High
$9,772.37
Fallon Health
Setting
Professional
Modifier
Global
Typical Low
$223.87
Median
$436.52
Typical High
$512.86
Harvard Pilgrim
Setting
Professional
Modifier
Global
Typical Low
$302.00
Median
$302.00
Typical High
$501.19
Mass General Brigham
Setting
Facility
Modifier
Global
Typical Low
$331.13
Median
$870.96
Typical High
$1,584.89
Mass General Brigham
Setting
Professional
Modifier
Global
Typical Low
$181.97
Median
$302.00
Typical High
$891.25
United
Setting
Facility
Modifier
Global
Typical Low
$181.97
Median
$302.00
Typical High
$363.08
United
Setting
Professional
Modifier
Global
Typical Low
$181.97
Median
$302.00
Typical High
$575.44

Where Massachusetts sits

The same service costs 3.9 times more in Alaska than in Vermont. Every bar is a state, most expensive first. Touch or drag across it to read any state, then open that state for its carriers and full range.

Massachusetts· 26th of 51

$302

AK $676VT $174

Median negotiated rate in each state, from every insurer that publishes one. States where no insurer publishes a rate for this service are not shown.